Evidence map›Paper›PMID 31242129›Full record

ArticleAutophagy2020

Hongkun Wu, Chang Liu, Qingyuan Yang, Chengde Xin, Juan Du, Fenyong Sun, Lin Zhou

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. The histone deacetylase family in health and disease.Signal transduction and targeted therapy · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. MircoRNAs predict and modulate responses to chemotherapy in leukemic patients.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  11. Review
  12. Article
  13. The ChickenGenes · 2024
    Article
  14. Review
  15. Article
  16. Exploring the time-dependent regulatory potential of microRNAs in breast cancer cells treated with proteasome inhibitors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hongkun WuDepartment of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, P.R. China.
Chang LiuDepartment of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, P.R. China.
Qingyuan YangDepartment of Clinical Laboratory Medicine, Tenth People's Hospital of Tongji University, Shanghai, P.R. China.
Chengde XinDepartment of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, P.R. China.
Juan DuDepartment of Hematology, The Myeloma & Lymphoma Center, Changzheng Hospital, Second Military Medical University, Shanghai, P.R. China.
Fenyong SunDepartment of Clinical Laboratory Medicine, Tenth People's Hospital of Tongji University, Shanghai, P.R. China.
Lin ZhouDepartment of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, P.R. China.
Second Military Medical University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is an incurable plasma cell malignancy with poor survival. Autophagy, a stress-responsive catabolic process mediated by lysosomal activity, plays a crucial role in the pathophysiology of MM. Growing evidence has indicated that dysregulated microRNAs (miRNAs) are associated with the aberrant autophagy in various human cancers. However, to date, few miRNAs have been reported to directly modulate autophagy in the pathobiology of MM. In this study, we investigated the role of

Indexed as

AnimalsApoptosisAutophagyBortezomibDown-RegulationHistone DeacetylasesHumansLysosomesMiceMicroRNAsMultiple MyelomaRepressor ProteinsUp-RegulationBortezomibHDAC4 protein, humanHdac5 protein, mouseHistone DeacetylasesMicroRNAsMIRN145a microRNA, mouseMIRN145 microRNA, humanRepressor ProteinsApoptosisautophagic cell deathautophagybortezomibHDAC4MIR145-3pmultiple myeloma

Identifiers

PMID31242129
PMCPMC7138223
OpenAlexW2953559774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.