Evidence map›Paper›PMID 31242021›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2019

Regulation of catecholamine release from the adrenal medulla is altered in deer mice (

Angela L Scott, Nicole A Pranckevicius, Colin A Nurse, Graham R Scott

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Fetal growth, high altitude, and evolutionary adaptation: a new perspective.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  8. Physiological Genomics of Adaptation to High-Altitude Hypoxia.Annual review of animal biosciences · 2021
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angela L ScottDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Nicole A PranckeviciusDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
Colin A NurseDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
Graham R ScottDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-altitude natives have evolved to overcome environmental hypoxia and provide a compelling system to understand physiological function during reductions in oxygen availability. The sympathoadrenal system plays a key role in responses to acute hypoxia, but prolonged activation of this system in chronic hypoxia may be maladaptive. Here, we examined how chronic hypoxia exposure alters adrenal catecholamine secretion and how adrenal function is altered further in high-altitude natives. Populations of deer mice (

Indexed as

AltitudeAdrenal MedullaAnimal DistributionAnimalsCatecholaminesGene Expression RegulationHypoxiaNicotineOxygenOxygen ConsumptionPeromyscusCatecholaminesNicotineOxygencatecholamineschromaffin cellsevolutionary physiologyoxygen chemosensitivity

Identifiers

PMID31242021
PMCPMC6766706
OpenAlexW2953596644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.