Evidence map›Paper›PMID 31242006›Full record

ArticleAmerican journal of public health2019

Targeting Youth to Prevent Later Substance Use Disorder: An Underutilized Response to the US Opioid Crisis.

Wilson M Compton, Christopher M Jones, Grant T Baldwin, Frances M Harding, Carlos Blanco, Eric M Wargo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wilson M ComptonWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Christopher M JonesWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Grant T BaldwinWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Frances M HardingWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Carlos BlancoWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Eric M WargoWilson M. Compton, Carlos Blanco, and Eric M. Wargo are with the National Institute on Drug Abuse, Bethesda, MD. At the time of the writing, Christopher M. Jones and Frances M. Harding were with the Substance Abuse and Mental Health Services Administration, Rockville, MD. Christopher M. Jones and Grant T. Baldwin are with the Centers for Disease Control and Prevention, Atlanta, GA.
Substance Abuse and Mental Health Services Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolving US opioid crisis is complex and requires myriad different interventions. These include reducing opioid overprescribing and curtailing the supply of illicit opioids, overdose rescue interventions, and treatment and recovery support services for those with opioid use disorders. To date, more distal primary prevention strategies that have an evidence base are underutilized. Yet, the impact of early environments on later substance use disorder risk is increasingly well understood, including knowledge of the mechanistic linkages between brain development and subsequent risk behaviors. Applying this developmental framework to prevention shows promise, and some middle-school interventions have demonstrated significant reductions in prescription opioid misuse. Reducing these risks of initial misuse of opioids may be the "ounce of prevention" that makes a substantial difference in a society now reeling from the worst drug crisis our country has seen. The challenge is to continue to develop and test promising distal interventions and to support implementation fidelity through frameworks that ensure their cultural appropriateness and sustainability. In addition, research is needed to develop new prevention strategies for adults, including patients with pain at risk for transitioning from prescription to illicit opioids.

Indexed as

AdolescentAdultCause of DeathEarly Intervention, EducationalForecastingHealth PromotionHumansOpioid-Related DisordersUnited StatesYoung Adult

Identifiers

PMID31242006
PMCPMC6595524
OpenAlexW2955807989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.