Evidence map›Paper›PMID 31241989›Full record

ReviewAmerican journal of physiology. Renal physiology2019

Sex differences in diabetes and kidney disease: mechanisms and consequences.

Blythe D Shepard

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 116 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Blythe D ShepardDepartment of Human Science, Georgetown University, Washington, District of Columbia.ORCID 0000-0001-6194-5268
Georgetown University · US

Funding

Elucidating the Role of Olfactory Receptor 1393 in Renal Glucose HandlingK01DK106400 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SHEPARD, BLYTHE D · 2016 to 2021
$657k
NIDDK NIH HHS K01 DK106400
6 · The paper itself

Abstract

Type 1 and type 2 diabetes, along with their accompanying hyperglycemia, are associated with a multitude of comorbidities including the development of diabetic kidney disease. Although the hallmarks of these metabolic disorders have been well characterized in population and animal studies, it is becoming increasingly apparent that diabetes manifests itself differently in men and women. This review summarizes the recent diabetic literature with a focus on known sex differences in clinical and preclinical studies. It explores the physiological differences of glucose handling and the development of diabetes between men and women. This review also uncovers potential mechanisms for these differences, honing in on the vital role that sex hormone signaling plays in the progression of diabetes and renal complications.

Indexed as

AnimalsDiabetes MellitusDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesFemaleHumansMaleSex Characteristicsdiabetesglucose reabsorptionsexsex hormones

Identifiers

PMID31241989
PMCPMC6732459
OpenAlexW2955802579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.