Evidence map›Paper›PMID 31241934›Full record

ArticleJournal of medicinal chemistry2019

Chemoproteomics of an Indole-Based Quinone Epoxide Identifies Druggable Vulnerabilities in Vancomycin-Resistant

Amogh Kulkarni, Isha Soni, Dhanashree S Kelkar, Allimuthu T Dharmaraja, Rathinam K Sankar, Gaurav Beniwal, Abinaya Rajendran, Sharvari Tamhankar, Sidharth Chopra, Siddhesh S Kamat and 1 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amogh Kulkarni
Isha SoniDivision of Microbiology , CSIR-Central Drug Research Institute , Sector 10, Janakipuram Extension, Sitapur Road , Lucknow 226021 , Uttar Pradesh , India.
Dhanashree S Kelkar
Allimuthu T Dharmaraja
Rathinam K Sankar
Gaurav Beniwal
Abinaya Rajendran
Sharvari Tamhankar
Sidharth ChopraDivision of Microbiology , CSIR-Central Drug Research Institute , Sector 10, Janakipuram Extension, Sitapur Road , Lucknow 226021 , Uttar Pradesh , India.
Harinath ChakrapaniORCID 0000-0002-7267-0906

Funding

DBT-Wellcome Trust India Alliance IA/I/15/2/502058
6 · The paper itself

Abstract

The alarming global rise in fatalities from multidrug-resistant

Indexed as

Anti-Bacterial AgentsBenzoquinonesDrug DiscoveryEpoxy CompoundsHumansIndolesModels, MolecularProteomicsStaphylococcal InfectionsStaphylococcus aureusVancomycinVancomycin ResistanceAnti-Bacterial AgentsBenzoquinonesEpoxy CompoundsIndolesquinoneVancomycin

Identifiers

PMID31241934
PMCPMC6660313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.