ArticleJournal of the American Geriatrics Society2019
Geriatric Syndromes in Older Adults Living with HIV and Cognitive Impairment.
Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Guideline
- Geriatric syndromes in women living with HIV.Current opinion in HIV and AIDS · 2026Review
- Predictors of mild cognitive impairment in older adults living with HIV and multimorbidity: a comparative analysis using logistic regression and decision tree models.Frontiers in public health · 2026Article
- Phase Angle Is Lower in Older Adults Living with HIV Compared to Geriatric Outpatients: A Case-Control Study.Journal of clinical medicine · 2025Article
- Plasma Inflammatory Biomarkers Link to Worse Cognition Among Africans With HIV.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Socioculturally Appropriate Internet-Based Geriatric Care Model for Older Adults Living With HIV: Experience-Based Co-Design Approach.JMIR aging · 2025Article
- The Performance of a New Multidimensional Frailty Index in Comparison to the Frailty Phenotype to Assess Frailty in People Living with HIV 50 Years of Age and Older in an Urban HIV Clinic.Journal of AIDS and HIV treatment · 2025Article
- Differences in people living with HIV (PLWH) population aged over 50 years old receiving antiretroviral therapy (ART).AIDS research and therapy · 2024Article
- The trend analysis of HIV and other sexually transmitted infections among the elderly aged 50 to 69 years from 1990 to 2030.Journal of global health · 2024Article
- A clinical overview of people living with HIV and genitourinary cancer care.Nature reviews. Urology · 2024Review
- Gender and coping with HIV: a qualitative study of older childhood sexual abuse survivors living with HIV.AIDS care · 2023Article
- Characterization of data-driven geriatric syndrome clusters in older people with HIV: a Mexican multicenter cross-sectional study.Lancet regional health. Americas · 2023Article
- Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIV.Journal of neurovirology · 2023Article
- Cognitive Health in Persons With Human Immunodeficiency Virus: The Impact of Early Treatment, Comorbidities, and Aging.The Journal of infectious diseases · 2023Article
- Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV.BMC geriatrics · 2023Article
- Treatment Regimens and Care Models for Older Patients Living with HIV: Are We Doing Enough?HIV/AIDS (Auckland, N.Z.) · 2023Review
- Frailty in older people living with HIV: current status and clinical management.BMC geriatrics · 2022Review
- The related factors of new HIV infection among older men in Sichuan, China: a case-control study.Epidemiology and infection · 2022Article
- The association between benzodiazepine use and greater risk of neurocognitive impairment is moderated by medical burden in people with HIV.Journal of neurovirology · 2022Article
- Factors associated to neurocognitive impairment in older adults living with HIV.European journal of medical research · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesNearly half of the population living with human immunodeficiency virus (HIV) in the United States is now older than 50 years with at least 6% over age 65. Between 35% and 50% live with mild to moderate cognitive impairment. Older persons living with HIV (PLWH) also have a substantial burden of HIV-associated non-acquired immunodeficiency syndrome medical conditions and are at risk for frailty, geriatric syndromes, and early mortality compared with HIV-uninfected peers. We sought to define the magnitude of geriatric conditions and multimorbidity in PLWH older than 60 years who are living with symptomatic cognitive impairment. In a subset of participants, we examined associations between these geriatric conditions.
designRetrospective cohort study.
settingHIV Elders Study at the University of California, San Francisco, Memory and Aging Center.
participantsParticipants were HIV infected, virally suppressed, 60 years or older, and clinically diagnosed with mild neurocognitive disorder (MND). MEASUREMENTS: We conducted standardized assessment of geriatric conditions and everyday function and investigated multimorbidity burden using the Veterans Aging Cohort Study (VACS) index.
resultsAmong 141 older PLWH with MND, 58% report incontinence, 55% meet criteria for pre-frailty, and a substantial proportion report dependence with instrumental activities of daily living (52%) or activities of daily living (41%). The mean VACS index score is 33 (standard deviation = 14), suggesting a 13.8% 5-year all-cause mortality risk.
conclusionsOlder PLWH with symptomatic cognitive impairment carry a substantial burden of other geriatric conditions. Our work supports the need for comprehensive geriatric systems of care for cognitively impaired individuals aging with HIV. J Am Geriatr Soc 67:1913-1916, 2019.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.