Evidence map›Paper›PMID 31241556›Full record

ArticleTransplantation2019

Center Variation and Risk Factors for Failure to Complete 6 Month Postdonation Follow-up Among Obese Living Kidney Donors.

Rhiannon D Reed, Paul A MacLennan, Brittany A Shelton, Margaux N Mustian, Justin Blackburn, Sharmene C Smith, Kristin B Terry, Raynesha Grant, Deirdre Sawinski, Jayme E Locke

Open access · greenAbstract readComparative Study
In one paragraph

Article in Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Living Kidney Donors' Residential Neighborhoods: Driver or Barrier of Postdonation Follow-Up?American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rhiannon D ReedComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Paul A MacLennanComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Brittany A SheltonComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Margaux N MustianComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Justin BlackburnDepartment of Health Policy and Management, Indiana University-Purdue University Indianapolis, Indianapolis, IN.
Sharmene C SmithComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Kristin B TerryComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Raynesha GrantComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Deirdre SawinskiComprehensive Transplant Center, University of Pennsylvania, Philadelphia, PA.
Jayme E LockeComprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
University of Alabama at Birmingham · US

Funding

CKD Risk Prediction among Obese Living Kidney DonorsR01DK113980 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LOCKE, JAYME ELIZABETH · 2018 to 2022
$3.4M
Long-term outcomes among living kidney donors with isolated medical abnormalitiesK23DK103918 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LOCKE, JAYME ELIZABETH · 2015 to 2019
$899k
NIDDK NIH HHS K23 DK103918NIDDK NIH HHS R01 DK113980
6 · The paper itself

Abstract

backgroundLiving kidney donors in the United States who were obese at donation are at increased risk of end-stage renal disease and may benefit from intensive postdonation follow-up. However, they are less likely to have complete follow-up data. Center variation and risk factors for incomplete follow-up are unknown.

methodsAdult living kidney donors with obesity (body mass index, ≥30 kg/m) at donation reported to the Scientific Registry of Transplant Recipients from January 2005 to July 2015 were included (n = 13 831). Donor characteristics were compared by recorded serum creatinine at 6 months postdonation, and multilevel logistic regression models were used to estimate odds of 6-month creatinine.

resultsAfter adjustment, older age, female sex, and donation after implementation of new center follow-up requirements were associated with higher odds of 6-month creatinine, with lower odds for obese donors with a history of smoking, biologically related donors, and at centers with higher total living donor volume. 23% of variation in recorded 6-month serum creatinine among obese donors was attributed to center (intraclass correlation coefficient: 0.232, P < 0.001). The adjusted probability of 6-month creatinine by center ranged from 10% to 91.5%.

conclusionsTremendous variation in recorded 6-month postdonation serum creatinine exists among obese living donors, with high volume centers having the lowest probability of follow-up. Moreover, individual-level characteristics such as age, sex, and relationship to recipient were associated with recorded 6-month creatinine. Given increased risk for end-stage renal disease among obese living donors, center-level efforts targeted specifically at increasing postdonation follow-up among obese donors should be developed and implemented.

Indexed as

Living DonorsNephrectomyAdultAftercareBiomarkersCreatinineDonor SelectionFemaleHealthcare DisparitiesHospitals, High-VolumeHospitals, Low-VolumeHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedBiomarkersCreatinine

Identifiers

PMID31241556
PMCPMC6597173
OpenAlexW2969623179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.