Evidence map›Paper›PMID 31241504›Full record

ArticleThe Journal of the Association of Nurses in AIDS Care : JANAC

Relationship of HIV Status and Fatigue, Cardiorespiratory Fitness, Myokines, and Physical Activity.

Allison R Webel, Trevor Jenkins, Christopher T Longenecker, Marianne Vest, Christine Horvat Davey, Jackson Currie, Rebecca Darrah, Paul Litman, Vitor Hugo Fernando de Oliveira, Richard A Josephson

Open access · greenAbstract read
In one paragraph

Article in The Journal of the Association of Nurses in AIDS Care : JANAC. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Allison R Webel
Trevor Jenkins
Christopher T Longenecker
Marianne Vest
Christine Horvat Davey
Jackson Currie
Rebecca Darrah
Paul Litman
Vitor Hugo Fernando de Oliveira
Richard A Josephson
Universidade Estadual de Londrina · BR

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
Impact of Physical Activity Routines and Dietary Intake on the Longitudinal Symptom Experience of the people living with HIV (PROSPER-HIV)R01NR018391 · NINR · UNIVERSITY OF WASHINGTON · PI WEBEL, ALLISON R · 2018 to 2022
$4.0M
Pericardial fat, inflammation, and structural heart disease in HIVK23HL123341 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LONGENECKER, CHRIS TODD · 2014 to 2018
$885k
NHLBI NIH HHS K23 HL123341NIAID NIH HHS P30 AI036219NINR NIH HHS R01 NR018391
6 · The paper itself

Abstract

People living with HIV (PLWH) experience high rates of fatigue, which can be improved with physical activity. We examined relationships between HIV infection, fatigue, cardiorespiratory fitness, physical activity, and myokines. Twenty PLWH and 20 HIV-uninfected adults completed a fatigue assessment, a maximal cardiometabolic exercise test, serum measures of myokines, and wore an accelerometer for 7 days. Measures were completed at baseline, 3 months, and 6 months. At baseline, PLWH had more fatigue (4.7 ± 2.6 vs. 2.8 ± 2.5, p = .01) and higher peak ventilatory efficiency (VE/VCO2; 33 ± 5.5 vs. 30.2 ± 2.5; p = .06). Half of PLWH engaged in at least one 10-minute bout of physical activity in the previous week, compared with control subjects (65%). Over time, HIV infection and fibroblast growth factor 21 were associated with fatigue (p < .05). People living with HIV have more fatigue and a higher ventilatory efficiency; expression of fibroblast growth factor 21 may underpin this relationship.

Indexed as

ExerciseAccelerometryAdultCardiorespiratory FitnessCase-Control StudiesExercise TestFatigueFemaleFibroblast Growth FactorsHIV InfectionsHumansInterleukin-15Interleukin-7Longitudinal StudiesMaleMiddle Agedfibroblast growth factor 21Fibroblast Growth FactorsInterleukin-15Interleukin-7

Identifiers

PMID31241504
PMCPMC7179736
OpenAlexW2910717906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.