ArticleFoodborne pathogens and disease2019
PulseNet: Entering the Age of Next-Generation Sequencing.
Article in Foodborne pathogens and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed.
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- Core genome and whole genome multi-locus sequence typing ofMicrobiology spectrum · 2026Article
- Antimicrobial resistantOne health (Amsterdam, Netherlands) · 2026Review
- Laboratory strategies for the identification of Burkholderia species: From classical phenotyping to advanced genomic and proteomic approaches.Antonie van Leeuwenhoek · 2026Review
- Pangenome dynamics and population structure of the zoonotic pathogen Salmonella enterica serotype Hadar.Nature communications · 2026Article
- From Paddock to Foal: Prevalence and Genotypic Diversity ofVeterinary sciences · 2026Article
- Antimicrobial resistance in nontyphoidalFrontiers in public health · 2026Article
- Interpreting antimicrobial resistance from bacterial whole-genome sequencing: prediction tools, database fragmentation, analytical trade-offs, and harmonized reporting.Frontiers in microbiology · 2026Review
- Evidence of diversification and geographic separation in a lineage ofMicrobial genomics · 2025Article
- Importance of Global Genomic Data Sharing to Prevent Illnesses Linked to Commercially Distributed Foods.Food safety (Tokyo, Japan) · 2025Article
- Genome-wide approaches to bacterial strain typing: a history and review of recent methodological advances.Current opinion in infectious diseases · 2025Review
- Longitudinal and cross-sectional sampling and whole genome sequencing ofApplied and environmental microbiology · 2025Article
- Genomic Modeling of an Outbreak of Multidrug-Resistant Shigella sonnei, California, USA, 2023-2024.Emerging infectious diseases · 2025Article
- Lessons from 5 Years of Routine Whole-Genome Sequencing for Epidemiologic Surveillance of Shiga Toxin-Producing Escherichia coli, France, 2018-2022.Emerging infectious diseases · 2025Article
- Whole-Genome Shotgun Sequencing from Chicken Clinical Tracheal Samples for Bacterial and Novel Bacteriophage Identification.Veterinary sciences · 2025Article
- Implementation of a high-throughput whole genome sequencing approach with the goal of maximizing efficiency and cost effectiveness to improve public health.Microbiology spectrum · 2024Article
- Foodborne Illness Complaint Systems Detect, and Restaurant Inspection Programs Prevent Restaurant-Associated Foodborne Illness Outbreaks.Foodborne pathogens and disease · 2024Article
- Antimicrobial resistance in multistate outbreaks of nontyphoidalJournal of clinical microbiology · 2024Article
- Molecular epidemiology of string test-positive Klebsiella pneumoniae isolates in Huzhou, China, 2020-2023.Frontiers in cellular and infection microbiology · 2024Article
- Antimicrobial resistance and genomic analysis ofFrontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 1996, PulseNet has served as the national laboratory-based surveillance system for the rapid detection of outbreaks caused by foodborne bacterial pathogens in the United States. For the past two decades, pulsed-field gel electrophoresis was the gold standard subtyping method for the pathogens tracked by PulseNet. A new gold standard is now being implemented with the introduction of cost-effective whole genome sequencing (WGS) for analysis of all the organisms tracked by PulseNet. This transformation is a major undertaking that touches every functional aspect of PulseNet, including laboratory workflows, data storage, analysis management and data interpretation, and language used to communicate information (sequence profile nomenclature system). The benefits of implementing WGS go beyond improved discrimination and precision of the data; it provides an opportunity to determine strain characteristics typically obtained through resource-intensive traditional methodologies, for example, species identification, serotyping, virulence, and antimicrobial resistance profiling, all of which can be consolidated into a single WGS workflow. Such a strategy represents a major shift in the workflows currently practiced in most public health laboratories, but one that brings opportunities for streamlining surveillance activities for the network as a whole. In this study, we provide a brief summary of PulseNet's evolution the past decade along with a general description of the challenges and opportunities that lie ahead.
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