Evidence map›Paper›PMID 31241152›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2019

ARBoR: an identity and security solution for clinical reporting.

Eric Venner, Mullai Murugan, Walker Hale, Jordan M Jones, Shan Lu, Victoria Yi, Richard A Gibbs

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eric VennerHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Mullai MuruganHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Walker HaleHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Jordan M JonesHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Shan LuHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Victoria YiHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Richard A GibbsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.

Funding

Genomic Architecture of Common Disease in Diverse Populations: WGS of Ongoing Hemorrhagic Stroke Study SupplementUM1HG008898 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2016 to 2020
$77.0M
DNA Sequencing Support for the eMERGE NetworkU01HG008664 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2015 to 2019
$10.9M
NHGRI NIH HHS U01 HG008664NHGRI NIH HHS UM1 HG008898
6 · The paper itself

Abstract

motivationClinical genome sequencing laboratories return reports containing clinical testing results, signed by a board-certified clinical geneticist, to the ordering physician. This report is often a PDF, but can also be a paper copy or a structured data file. The reports are frequently modified and reissued due to changes in variant interpretation or clinical attributes. MATERIALS AND

methodsTo precisely track report authenticity, we developed ARBoR (Authenticated Resources in a Hashed Block Registry), an application for tracking the authenticity and lineage of versioned clinical reports even when they are distributed as PDF or paper copies. ARBoR tracks clinical reports as cryptographically signed hash blocks in an electronic ledger file, which is then exactly replicated to many clients.

resultsARBoR was implemented for clinical reporting in the Human Genome Sequencing Center Clinical Laboratory, initially as part of the National Institute of Health's Electronic Medical Record and Genomics (eMERGE) project.

conclusionsTo date, we have issued 15 205 versioned clinical reports tracked by ARBoR. This system has provided us with a simple and tamper-proof mechanism for tracking clinical reports with a complicated update history.

Indexed as

Computer SecurityGenetic TestingGenomicsLaboratoriesMedical RecordsClinical Laboratory TechniquesGenome, HumanHumansOrganizational Case Studiesclinical genomicsgenetic report

Identifiers

PMID31241152
PMCPMC6798556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.