Evidence map›Paper›PMID 31240991›Full record

ArticleOrganogenesis2019

Mesenchymal Wnt/β-catenin signaling induces Wnt and BMP antagonists in dental epithelium.

Xiaoyan Chen, Jing Liu, Nan Li, Yu Wang, Nan Zhou, Lei Zhu, Yiding Shi, Yingzhang Wu, Jing Xiao, Chao Liu

Open access · bronzeAbstract read
In one paragraph

Article in Organogenesis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Ectopic Activation ofInternational journal of molecular sciences · 2024
    Article
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  7. Loss of Stat3 in OsterixCell & bioscience · 2023
    Article
  8. Tooth number abnormality: from bench to bedside.International journal of oral science · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoyan Chena Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Jing Liua Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Nan Lia Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Yu Wanga Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Nan Zhoua Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Lei Zhua Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Yiding Shia Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Yingzhang Wua Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Jing Xiaoa Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.
Chao Liua Dalian key laboratory of basic research in oral medicine and Department of Oral Pathology College of Stomatology, Dalian Medical University , Dalian , China.ORCID 0000-0002-3584-0224
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies indicated that the elevated mesenchymal Wnt/β-catenin signaling deprived dental mesenchyme of odontogenic fate. By utilizing

Indexed as

Wnt Signaling PathwayAnimalsbeta CateninBone Morphogenetic ProteinsCell ProliferationCell SurvivalCore Binding Factor Alpha 1 SubunitEpitheliumFemaleFibroblast Growth Factor 3Gene Expression Regulation, DevelopmentalGenotypeMaleMesodermMiceMolarbeta CateninBone Morphogenetic ProteinsCore Binding Factor Alpha 1 SubunitCTNNB1 protein, mouseFgf3 protein, mouseFibroblast Growth Factor 3Msx1 protein, mouseMSX1 Transcription FactorRunx2 protein, mouseWnt1 ProteinWnt1 protein, mouseantagonistodontogenic fatetissue interactiontooth developmentWnt/β-catenin signaling

Identifiers

PMID31240991
PMCPMC6668654
OpenAlexW2955290426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.