Evidence map›Paper›PMID 31240877›Full record

ReviewAnnals of laboratory medicine2019

Current Aspects of Clonal Hematopoiesis: Implications for Clinical Diagnosis.

Kristin Karner, Tracy I George, Jay L Patel

Abstract readReview
In one paragraph

Review in Annals of laboratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristin KarnerDepartment of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0002-1107-8650
Tracy I GeorgeDepartment of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT, USA. tracy.george@path.utah.edu.ORCID https://orcid.org/0000-0001-5478-7847
Jay L PatelDepartment of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0001-6531-3225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The broad dissemination of next-generation sequencing capability has increased recognition of clonal hematopoiesis in various clinical settings. In hematologically normal individuals, somatic mutations may occur at an increasing frequency with age in genes that are also commonly mutated in overt myeloid malignancies such as AML and MDS (e.g.,

Indexed as

Diagnosis, DifferentialDioxygenasesDNA-Binding ProteinsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AGene FrequencyHematologic NeoplasmsHematopoiesisHigh-Throughput Nucleotide SequencingHumansMutationMyeloproliferative DisordersProto-Oncogene ProteinsDioxygenasesDNA-Binding ProteinsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanProto-Oncogene ProteinsTET2 protein, humanClonal cytopenias of undetermined significanceClonal hematopoiesisClonal hematopoiesis of indeterminate potentialIdiopathic cytopenias of undetermined significance

Identifiers

PMID31240877
PMCPMC6660325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.