Evidence map›Paper›PMID 31240876›Full record

ReviewCancer medicine2019

Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma-related epilepsy.

Shuli Liang, Xing Fan, Ming Zhao, Xia Shan, Wenling Li, Ping Ding, Gan You, Zhen Hong, Xuejun Yang, Guoming Luan and 31 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Glioblastoma survival prediction through MRI and clinical data integration with transfer learning.International journal of computer assisted radiology and surgery · 2026
    Article
  4. Article
  5. Article
  6. The molecular landscape of glioblastoma-associated epilepsy.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
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  16. Review
  17. Article
  18. Article
  19. The evaluation of six genes combined value in glioma diagnosis and prognosis.Journal of cancer research and clinical oncology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors at 20 institutions in 1 country.

Shuli LiangDepartment of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China.
Xing FanDepartment of Neuroelectrophysiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Ming ZhaoDepartment of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, China.
Xia ShanDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wenling LiDepartment of Neurosurgery, Second Affiliated Hospital, Hebei Medical University, Shijiazhuang, China.
Ping DingDepartment of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China.
Gan YouDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhen HongDepartment of Neurology, Shanghai Huashan Hospital, Fudan University, Shaihai, China.
Xuejun YangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Guoming LuanDepartment of Neurosurgery, Beijing Sanbo Hospital, Capital Medical University, Beijing, China.
Wenbin MaDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hui YangDepartment of Neurosurgery, Second Affiliated Hospital, Army Medical University, Chongqing, China.
Yongpin YouDepartment of Neurosurgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tianming YangDepartment of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing, China.
Liang LiDepartment of Neurosurgery, First Affiliated Hospital, Beijing University, Beijing, China.
Weiping LiaoDepartment of Neurology, Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Lei WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xun WuDepartment of Neurology, First Affiliated Hospital, Beijing University, Beijing, China.
Xinguang YuDepartment of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China.ORCID 0000-0003-4925-8320
Jianguo ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Qing MaoDepartment of Neurosurgery, Huaxi Hospital, Sichuan University, Chengdu, China.
Yuping WangDepartment of Neurology, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China.
Wenbin LiDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Xuefeng WangDepartment of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Chuanlu JiangDepartment of Neurosurgery, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Xiaoyan LiuPediatric Department, First Affiliated Hospital, Beijing University, Beijing, China.
Songtao QiDepartment of Neurosurgery, Nanfang Hospital, Nanfang Medical University, Guangzhou, China.
Xingzhou LiuEpilepsy Center, Shanghai Deji Hospital, Shanghai, China.
Yan QuDepartment of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Jiwen XuDepartment of Functional Neurosurgery, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Weimin WangDepartment of Neurosurgery, Guangzhou Military General Hospital, Guangzhou, China.
Zhi SongDepartment of Neurology, Xiangya Third Hospital, Center South University, Changsha, China.
Jinsong WuDepartment of Neurosurgery, Shanghai Huashan Hospital, Fudan University, Shanghai, China.
Zhixiong LiuDepartment of Neurosurgery, Xiangya Hospital, Center South University, Changsha, China.
Ling ChenDepartment of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China.
Yuanxiang LinDepartment of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Jian ZhouDepartment of Neurosurgery, Beijing Sanbo Hospital, Capital Medical University, Beijing, China.
Xianzeng LiuDepartment of Neurology, Peking University International Hospital, Beijing, China.
Wei ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Shichuo LiChina Association Against Epilepsy (CAAE), Beijing, China.
Tao JiangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-7008-6351
Capital Medical University · CNPeking University · CNChinese PLA General Hospital · CNCentral South University · CNFudan University · CNHebei Medical University · CNAir Force Medical University · CNArmy Medical University · CNChina Association for Science and Technology · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFirst Affiliated Hospital of Chinese PLA General Hospital · CNFujian Medical University · CNGeneral Hospital of Guangzhou Military Command · CNHarbin Medical University · CNJiangsu Province Hospital · CNNanfang Hospital · CNSecond Affiliated Hospital of Guangzhou Medical University · CNShanghai Jiao Tong University · CNSichuan University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlioma-related epilepsy (GRE) is defined as symptomatic epileptic seizures secondary to gliomas, it brings both heavy financial and psychosocial burdens to patients with diffuse glioma and significantly decreases their quality of life. To date, there have been no clinical guidelines that provide recommendations for the optimal diagnostic and therapeutic procedures for GRE patients.

methodsIn March 2017, the Joint Task Force for GRE of China Association Against Epilepsy and Society for Neuro-Oncology of China launched the guideline committee for the diagnosis and treatment of GRE. The guideline committee conducted a comprehensive review of relevant domestic and international literatures that were evaluated and graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence, and then held three consensus meetings to discuss relevant recommendations. The recommendations were eventually given according to those relevant literatures, together with the experiences in the diagnosis and treatment of over 3000 GRE cases from 24 tertiary level hospitals that specialize in clinical research of epilepsy, glioma, and GRE in China.

resultsThe manuscript presented the current standard recommendations for the diagnostic and therapeutic procedures of GRE.

conclusionsThe current work will provide a framework and assurance for the diagnosis and treatment strategy of GRE to reduce complications and costs caused by unnecessary treatment. Additionally, it can serve as a reference for all professionals involved in the management of patients with GRE.

Indexed as

AnticonvulsantsBrain NeoplasmsChinaDrug TherapyEpilepsyEvidence-Based MedicineGliomaHumansNeurosurgical ProceduresPractice Guidelines as TopicQuality of LifeAnticonvulsantsadult diffuse gliomadiagnosis and treatmentepilepsyguideline

Identifiers

PMID31240876
PMCPMC6712518
OpenAlexW2954776077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.