ArticleJournal of cellular and molecular medicine2019
Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis.
Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Trial
- Review
- Establishment and validation of a risk prediction model for acute ischemic stroke in a carotid artery plaque population.Quantitative imaging in medicine and surgery · 2025Article
- A cross-sectional study of the association between blood metal mixtures exposure and hyperuricemia.Clinical rheumatology · 2024Article
- High serum uric acid is a risk factor for arterial stiffness in a Chinese hypertensive population: a cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Gender differences in all-cause and cardiovascular mortality among US adults: from NHANES 2005-2018.Frontiers in cardiovascular medicine · 2024Article
- Distribution of Arteriosclerotic Vessels in Patients with Arteriosclerosis and the Differences of Serum Lipid Levels Classified by Different Sites.International journal of general medicine · 2024Article
- Prognostic Significance of Uric Acid Levels in Intracerebral Hemorrhage Patients.Neuropsychiatric disease and treatment · 2024Article
- High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.Journal of atherosclerosis and thrombosis · 2023Article
- Dioscin Ameliorates Hyperuricemia-Induced Atherosclerosis by Modulating of Cholesterol Metabolism through FXR-Signaling Pathway.Nutrients · 2022Article
- The dose-response relationship of serum uric acid with Dyslipidaemia and its components: a cross-sectional study of a Chinese multi-ethnic cohort.Lipids in health and disease · 2022Article
- Association Between Serum Uric Acid and Intracranial Arterial Stenosis in a Korean Population: A Secondary Analysis Based on a Cross-Sectional Study.Frontiers in neurology · 2022Article
- Fibrinolytic markers could be useful predictors of severity in patients with pulmonary arterial hypertension: a retrospective study.Thrombosis journal · 2021Article
- Variation in serum urate levels in the absence of gout and urate lowering therapy.BMC rheumatology · 2021Article
- Body roundness index is a superior indicator to associate with the cardio-metabolic risk: evidence from a cross-sectional study with 17,000 Eastern-China adults.BMC cardiovascular disorders · 2021Article
- Hyperuricemia Is Associated with Left Ventricular Dysfunction and Inappropriate Left Ventricular Mass in Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2020Article
- Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study.Scientific reports · 2020Article
- Study of association of serum uric acid with albuminuria and carotid atherosclerosis in type 2 diabetes mellitus patients.Journal of family medicine and primary care · 2019Article
- Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis.Journal of cellular and molecular medicine · 2019Article
- Uric Acid and Atherosclerosis in Patients with Chronic Kidney Disease: Recent Progress, Mechanisms, and Prospect.Kidney diseases (Basel, Switzerland)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiterritorial atherosclerosis has dramatically increased annual risk of adverse cardiovascular events than atherosclerotic disease with single-artery affected. Serum uric acid (SUA) is an important predictor of stroke and atherosclerosis; however, which is supported by few direct evidence based on cohort studies. A prospective cohort study including 2644 North Chinese adults aged ≥40 years was performed in 2010-2012 to investigate the association between SUA and multiterritorial vascular stenosis. Hyperuricaemia was defined as SUA levels >6 and >7 mg/dL for males and females, respectively. All participants underwent twice transcranial Doppler (TCD) and bilateral carotid duplex ultrasound to evaluate intracranial artery stenosis (ICAS) and extracranial arterial stenosis (ECAS) and peripheral arterial disease (PAD) was determined by ankle-brachial index (ABI) on January 2010 and January 2012 based on regular health check-ups. The cumulative incidence of vascular stenosis was significantly higher in subjects with hyperuricaemia than in those without hyperuricaemia (54.1% vs. 34.7%, P < 0.001). The adjusted odds ratios (ORs) with 95% confidence intervals (CIs) for new on-set vascular stenosis due to hyperuricaemia and a 1-mg/dL change in SUA level were 1.75 (1.32-2.31) and 1.29 (1.21-1.38), respectively. Furthermore, in the gender-stratified analysis, the association between SUA levels and ICAS was statistically significant in males (OR: 2.02; 95% CI: 1.18-3.46), but not females (OR: 0.85, 95% CI: 0.41-1.76, P for interaction: 0.026).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.