ArticleThe Journal of physiology2019
Using optically pumped magnetometers to measure magnetoencephalographic signals in the human cerebellum.
Article in The Journal of physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 64 citations in OpenAlex.
- From Contrasts to Representations: Rethinking fMRI Approaches for Cortico-Cerebellar Networks.Cerebellum (London, England) · 2026Review
- Quantifying cerebellar signal detectability in MEG and EEG in epilepsy using anatomically informed source modeling.NeuroImage · 2026Article
- Environment-Driven Synthetic Baseline Analysis and Optimization in Joint Measurement OPM-MEG Arrays.Bioengineering (Basel, Switzerland) · 2026Article
- Efficacy of Optically Pumped Magnetometers in Detecting Activity From the Cerebellar Cortex.Human brain mapping · 2026Article
- Movement Related Beta-Band Modulation with OPM-MEG: A Pilot Study.Brain topography · 2025Article
- SPM-30 years and beyond.Cerebral cortex (New York, N.Y. : 1991) · 2025Review
- Superconducting Quantum Magnetometers for Brain Investigations.Sensors (Basel, Switzerland) · 2025Review
- Functional interaction between posterior cerebellar lobes and secondary somatosensory cortex during somatosensory mismatch detection.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Early insights into eyeblink conditioning using optically pumped magnetometer-based MEG.Frontiers in human neuroscience · 2025Article
- Towards a 384-channel magnetoencephalography system based on optically pumped magnetometers.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Decoding the Temporal Structures and Interactions of Multiple Face Dimensions Using Optically Pumped Magnetometer Magnetoencephalography (OPM-MEG).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A novel, robust, and portable platform for magnetoencephalography using optically-pumped magnetometers.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Applications of OPM-MEG for translational neuroscience: a perspective.Translational psychiatry · 2024Review
- Article
- A Novel, Robust, and Portable Platform for Magnetoencephalography using Optically Pumped Magnetometers.bioRxiv : the preprint server for biology · 2024Article
- Yttrium-Iron Garnet Magnetometer in MEG: Advance towards Multi-Channel Arrays.Sensors (Basel, Switzerland) · 2023Article
- Electrophysiological activity from over the cerebellum and cerebrum during eye blink conditioning in human subjects.Physiological reports · 2023Article
- Combining magnetoencephalography with telemetric streaming of intracranial recordings and deep brain stimulation-A feasibility study.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Spin exchange optically pumped nuclear spin self compensation system for moving magnetoencephalography measurement.Biomedical optics express · 2022Article
- Magnetoencephalography with optically pumped magnetometers (OPM-MEG): the next generation of functional neuroimaging.Trends in neurosciences · 2022Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
key pointsThe application of conventional cryogenic magnetoencephalography (MEG) to the study of cerebellar functions is highly limited because typical cryogenic sensor arrays are far away from the cerebellum and naturalistic movement is not allowed in the recording. A new generation of MEG using optically pumped magnetometers (OPMs) that can be worn on the head during movement has opened up an opportunity to image the cerebellar electrophysiological activity non-invasively. We use OPMs to record human cerebellar MEG signals elicited by air-puff stimulation to the eye. We demonstrate robust responses in the cerebellum. OPMs pave the way for studying the neurophysiology of the human cerebellum. ABSTRACT: We test the feasibility of an optically pumped magnetometer-based magnetoencephalographic (OP-MEG) system for the measurement of human cerebellar activity. This is to our knowledge the first study investigating the human cerebellar electrophysiology using optically pumped magnetometers. As a proof of principle, we use an air-puff stimulus to the eyeball in order to elicit cerebellar activity that is well characterized in non-human models. In three subjects, we observe an evoked component at approx. 50 ms post-stimulus, followed by a second component at approx. 85-115 ms post-stimulus. Source inversion localizes both components in the cerebellum, while control experiments exclude potential sources elsewhere. We also assess the induced oscillations, with time-frequency decompositions, and identify additional sources in the occipital lobe, a region expected to be active in our paradigm, and in the neck muscles. Neither of these contributes to the stimulus-evoked responses at 50-115 ms. We conclude that OP-MEG technology offers a promising way to advance the understanding of the information processing mechanisms in the human cerebellum.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.