ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2019
Clinical and anorectal manometry profile of patients with functional constipation and constipation-predominant irritable bowel syndrome.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Indian consensus statements on irritable bowel syndrome in adults: A guideline by the Indian Neurogastroenterology and Motility Association and jointly supported by the Indian Society of Gastroenterology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Guideline
- High-resolution anorectal manometry in chronic constipation-Defining dysfunction beyond diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- High-resolution anorectal manometry profile in patients with chronic constipation versus control.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- What is new in Rome V?: Redefining diagnostic criteria and clinical pathways in disorders of gut-brain interaction.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Diagnostic Accuracy of Anorectal Manometry in Identifying Dyssynergic Defecation among Chronic Constipation Patients.Annals of African medicine · 2026Observational
- Prevalence, clinical significance and predictors of small intestinal bacterial overgrowth and elevated fecal calprotectin in refractory irritable bowel syndrome: Insights from a prospective cross-sectional study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation.World journal of gastrointestinal pharmacology and therapeutics · 2026Review
- The road to Rome IV and beyond: Evolution, refinements and future considerations for the Rome criteria for functional gastrointestinal disorders.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Self-Reported Food Triggers and Food Fears Impact Nutrient Intake and Quality of Life in Patients with Irritable Bowel Syndrome and Functional Dyspepsia.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- Rome Foundation Working Team Report on overlap in disorders of gut-brain interaction.Nature reviews. Gastroenterology & hepatology · 2025Review
- The Clinical Utility of Anorectal Manometry: A Review of Current Practices.Gastro hep advances · 2025Review
- Morphological Changes of the Pituitary Gland in Patients with Irritable Bowel Syndrome Using Magnetic Resonance Imaging.Journal of imaging · 2024Article
- Colorectal motility patterns and psychiatric traits in functional constipation and constipation-predominant irritable bowel syndrome: A study from China.World journal of gastroenterology · 2023Article
- Clinical Characteristics of Adult Functional Constipation Patients with Rectoanal Areflexia and Their Response to Biofeedback Therapy.Diagnostics (Basel, Switzerland) · 2023Article
- Behavioral Intervention in Children with Functional Abdominal Pain Disorders: A Promising Option.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
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3 authors.
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Abstract
backgroundFunctional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C) have significant healthcare impact. Clinical and investigative data of patients with these disorders in Indian population is scarce. We aimed to compare the clinical and anorectal manometric profile of patients with FC and IBS-C.
methodsConsecutive patients with chronic constipation undergoing anorectal manometry (ARM) and balloon expulsion test (BET) were enrolled. Thirty healthy volunteers served as controls (HC). Functional defecatory disorder (FDD) was diagnosed according to ROME IV criteria if both ARM and BET were abnormal.
resultsOf the 231 patients enrolled (median age 47 years, 87.8% males), FC and IBS-C were diagnosed in 132 (57.1%) and 99 (42.9%) patients, respectively. Significant clinical differences between FC and IBS-C patients included older age, lower stool frequency/week, higher frequency of straining, and greater frequency of incomplete evacuation (p < 0.001). ARM revealed abnormal defecatory pattern in 55.3% (n = 73) FC patients and 47.5% (n = 47) IBS-C patients. Of them, 54.7% (40/73) of FC patients had inadequate defecatory propulsion while 89.4% (42/47) of the IBS-C patients had dyssynergic defecation (p < 0.001). Abnormal BET was seen in 67.4% of FC patients and 43.4% of IBS-C patients. Thus, FDD was diagnosed in 55.3% and 46.5% of FC and IBS-C patients, respectively. Rectal hyposensitivity was present in 60.6% of FC patients compared with 2% of IBS-C patients (p < 0.001).
conclusionsThere were significant differences in clinical and manometric profile of FC and IBS-C patients. Compared with IBS-C patients, FC patients were older, had higher prevalence of FDD, less often had dyssynergic defecation, and had higher prevalence of rectal hyposensitivity.
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