ArticleInternational journal of hematology2019
Molecular characteristics of thalassemia and hemoglobin variants in prenatal diagnosis program in northern Thailand.
Article in International journal of hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Prevalence of Alpha(α)-Thalassemia in Southeast Asia (2010-2020): A Meta-Analysis Involving 83,674 Subjects.International journal of environmental research and public health · 2020Pooled it
- Prevalence of Severe Thalassemia and Performance of Prenatal Screening Tests Among Pregnant Women at Siriraj Thalassemia Center in Thailand.Clinical and translational science · 2026Article
- Subtype Distribution and Mutation Spectrum of Thalassemia in Children Under 10 Years in Northern Vietnam.Mediterranean journal of hematology and infectious diseases · 2026Article
- A New Method for Screening Thalassemia Patients Using Mid-Infrared Spectroscopy.Diagnostics (Basel, Switzerland) · 2025Article
- Clinical and hematological characteristics of beta-plus thalassemia and uncommon beta-chain hemoglobin variants in Northern Thailand.Annals of medicine · 2025Article
- Phenotypic Variability and Hematological Characterization of βJournal of clinical medicine research · 2025Article
- Survival and causes of death in patients with alpha and beta-thalassemia in Northern Thailand.Annals of medicine · 2024Article
- Thalassemia screening by third-generation sequencing: Pilot study in a Thai population.Obstetric medicine · 2024Article
- Prevalence of thalassemia-carrier couples and fertility risk assessment.International journal of hematology · 2024Article
- Revisiting and updating molecular epidemiology of α-thalassemia mutations in Thailand using MLPA and new multiplex gap-PCR for nine α-thalassemia deletion.Scientific reports · 2023Article
- Gene Mutation Spectrum among Alpha-Thalassaemia Patients in Northeast Peninsular Malaysia.Diagnostics (Basel, Switzerland) · 2023Article
- Molecular characterization of hemoglobinopathies and thalassemias in Northern Guangdong Province, China.Medicine · 2021Article
- Comparison of cord blood hematological parameters among normal, α-thalassemia, and β-thalassemia fetuses between 17 and 38 weeks of gestation.Scientific reports · 2021Article
- Alpha-hemoglobin-stabilizing protein (AHSP): a modulatory factor in β-thalassemia.International journal of hematology · 2020Review
- Prenatal diagnosis of α- and β-thalassemias in southern Thailand.International journal of hematology · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular analysis of globin genes is an essential process for prenatal diagnosis (PND) of severe thalassemia. This study aimed to describe the molecular characteristics of thalassemia and hemoglobin (Hb) variants in PND program in northern Thailand. The type and frequency of globin gene mutations from 1290 couples at risk of fetal severe thalassemia diseases that were tested at Thalassemia Laboratory at Chiang Mai University from 2012 to 2017 were retrospectively reviewed. The PND program detected 444 (34.4%), 196 (15.2%) and 642 (49.8%) couples at risk of fetal Hb Bart's hydrops fetalis, beta-thalassemia major (BTM) and beta-thalassemia/Hb E disease, respectively. Coinheritance of more than one type of thalassemia was common and eight (0.6%) couples were at risk of two types of severe thalassemia. There were two types of alpha
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