ArticleMycopathologia2019
Investigation on Microecology of Hair Root Fungi in Androgenetic Alopecia Patients.
Article in Mycopathologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- The effects of caffeine and adenosine on the microbiome and lipidome of the scalp.International journal of cosmetic science · 2025Trial
- Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights.International journal of dermatology · 2026Review
- Scalp Microbiota Dysbiosis in Seborrheic Alopecia and Restoration Following Herbal Extract Shampoo Intervention.Microorganisms · 2026Article
- Viable vs. Nonviable Microbiota Evaluation of the Hair Follicle and Scalp Microbiome.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Lifestyle factors affecting the pathogenesis of androgenetic alopecia: a literature review.Frontiers in public health · 2026Review
- Double Challenges for Scalp Health: A Review of the Pathogenesis and Treatment Strategies of Coexistence of Seborrheic Dermatitis and Androgenetic Alopecia.Dermatology research and practice · 2026Review
- Microbial dysbiosis and its diagnostic potential in androgenetic alopecia: insights from multi-kingdom sequencing and machine learning.mSystems · 2025Article
- Immune and Non-immune Interactions in the Pathogenesis of Androgenetic Alopecia.Clinical reviews in allergy & immunology · 2025Review
- Conductive Bio-Harvesting Tonic (CBT) with an Anti-Dandruff Effect Enhances Hair Growth by Utilizing Naturally Generated Electric Energy during Human Activities.Journal of microbiology and biotechnology · 2024Article
- Characteristics of Malassezia furfur at various pH and effects of Malassezia lipids on skin cells.Applied microbiology and biotechnology · 2024Article
- Illuminating microflora: shedding light on the potential of blue light to modulate the cutaneous microbiome.Frontiers in cellular and infection microbiology · 2024Review
- The Gut and Skin Microbiome in Alopecia: Associations and Interventions.The Journal of clinical and aesthetic dermatology · 2023Review
- Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia.Microorganisms · 2021Article
- The Potential Relevance of the Microbiome to Hair Physiology and Regeneration: The Emerging Role of Metagenomics.Biomedicines · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study focused on the differences in hairy root fungal microecology between androgenetic alopecia patients and healthy individuals.
methodsLight microscopy was used to observe the morphology of hairy roots. Morphological observations were also performed in the positive specimens using scanning electron microscopy and transmission electron microscopy. The high-throughput sequencing method was used to detect the fungal microecology of hairy roots at different sites. Moreover, the comparison of fungal loads of Malassezia in different group and scalp area were tested by PCR.
resultsThe fungi in the hair root observed by optical microscopy are mainly Malassezia yeast. The positive rate of Malassezia in the hair loss group (60%) was higher than that in the control group (40%). The detection efficiency of Malassezia examined by scanning electron microscopy was higher than that by light microscopy. Results acquired from high-throughput molecular sequencing of fungi suggested that Ascomycota was the dominant species, whereas in the occipital hair roots of the control group Basidiomycota was the dominant species in the hair loss group. Malassezia followed by Trichosporon were the most abundant fungal genera. The changes in abundance at the top and occipital region of the control group were more significant than those of the genus Fusarium, followed by Epicoccum and Malassezia. The load of Malassezia located on calvaria in the alopecia group was significantly higher than that in the control group. In the alopecia group, the load of Malassezia on the scalp was higher than that on the occipital region. The load of Malassezia globosa and Malassezia restricta in the hair loss group was higher on calvaria and occipital areas.
conclusionMalassezia had a positive correlation with the incidence of androgenic alopecia.
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