Evidence map›Paper›PMID 31240434›Full record

ArticleWorld journal of surgery2019

Association Between Compliance to an Enhanced Recovery Protocol and Outcome After Elective Surgery for Gastric Cancer. Results from a Western Population-Based Prospective Multicenter Study.

Luca Gianotti, Uberto Fumagalli Romario, Stefano De Pascale, Jacopo Weindelmayer, Valentina Mengardo, Marta Sandini, Andrea Cossu, Paolo Parise, Riccardo Rosati, Lapo Bencini and 10 more

Abstract read
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In one paragraph

Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 2 countries.

Luca Gianotti *Department of Surgery, School of Medicine and Surgery, San Gerardo Hospital, Milano - Bicocca University, Monza, Italy.
Uberto Fumagalli Romario *Digestive Surgery, European Institute of Oncology IRCCS, Milan, Italy. ubertofumagalliromario@gmail.com.
Stefano De PascaleDigestive Surgery, European Institute of Oncology IRCCS, Milan, Italy.
Jacopo WeindelmayerGeneral and Esophagogastric Surgery, University of Verona, Verona, Italy.
Valentina MengardoGeneral and Esophagogastric Surgery, University of Verona, Verona, Italy.
Marta SandiniDepartment of Surgery, School of Medicine and Surgery, San Gerardo Hospital, Milano - Bicocca University, Monza, Italy.
Andrea CossuDigestive Surgery, San Raffaele Hospital, San Raffaele Vita e Salute University, Milan, Italy.
Paolo PariseDigestive Surgery, San Raffaele Hospital, San Raffaele Vita e Salute University, Milan, Italy.
Riccardo RosatiDigestive Surgery, San Raffaele Hospital, San Raffaele Vita e Salute University, Milan, Italy.
Lapo BenciniOncologic and Robotic Surgery, Department of Oncology, Azienda Ospedaliero - Universitaria Careggi, Florence, Italy.
Andrea CorattiOncologic and Robotic Surgery, Department of Oncology, Azienda Ospedaliero - Universitaria Careggi, Florence, Italy.
Giovanni ColomboDepartment of Surgery, School of Medicine and Surgery, San Gerardo Hospital, Milano - Bicocca University, Monza, Italy.
Federica GalliDepartment of Surgery, ASST Settelaghi, Varese, Italy.
Stefano RauseiDepartment of Surgery, ASST Valle Olona, Gallarate, Italy.
Francesco CasellaGeneral Surgery, Vannini-Figlie di San Camillo Hospital, Rome, Italy.
Andrea SansonettiGeneral Surgery, Vannini-Figlie di San Camillo Hospital, Rome, Italy.
Dario MaggioniGeneral Surgery 3, ASST-Monza, Desio Hospital, Desio, Italy.
Andrea CostanziGeneral Surgery 3, ASST-Monza, Desio Hospital, Desio, Italy.
Davide P BernasconiCentre of Biostatistics for Clinical Epidemiology, School of Medicine and Surgery, Milano-Bicocca University, Monza, Italy.
Giovanni De ManzoniGeneral and Esophagogastric Surgery, University of Verona, Verona, Italy.
University of Milano-Bicocca · ITUniversity of Verona · ITVita-Salute San Raffaele University · ITAzienda Ospedaliera San Gerardo · ITAzienda Ospedaliero-Universitaria Careggi · ITEuropean Institute of Oncology · ITAzienda Ospedaliera Sant’Antonio Abate di Gallarate · ITFondazione Audiologica Varese · ITIRCCS San Camillo Hospital · ITNini Hospital · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between compliance to an enhanced recovery protocol (ERAS) and outcome after surgery for gastric cancer has been poorly investigated, particularly in Western patients. The aim of the study was to evaluate whether the rate of adherence to the ERAS program was correlated with outcome and time of discharge.

methodsA prospective, observational, multicenter study was designed to be performed at Italian referral centers for gastric surgery. The protocol was discussed and approved by the Italian Research Group on Gastric Cancer. Twenty-three ERAS domains were applied. A multivariate logistic regression was used to assess the association between ERAS compliance and overall and major complication rates. The Poisson regression model (measured as mean ratios) was used to assess the association of ERAS compliance rate and length of stay (LOS).

resultsEight centers participated and 290 subjects with a median age of 73 years were enrolled. The overall rates of adherence to pre-, intra-, and postoperative ERAS items were 69.8%, 60.3%, and 82.5%, respectively. At the multivariate model, there was an association between overall rate of morbidity and an overall ERAS compliance rate greater than 70% (OR 0.413; 95% CI 0.235-0.7240; P 0.002). A similar association was found for major complications (OR 0.328; 95% CI 0.151-0.709; P 0.005). The Poisson regression showed that in patients with ERAS compliance rate >70%, LOS was reduced of approximately 20% (mean ratio 0.812; 95% CI 0.694-0.950; P 0.009).

conclusionsThese results suggest a moderate compliance to an ERAS program and a significant association between adherence and outcomes.

Indexed as

GastrectomyLength of StayPatient ComplianceAgedAge FactorsComorbidityElective Surgical ProceduresFemaleHumansItalyMaleMiddle AgedPatient DischargePoisson DistributionPostoperative ComplicationsPostoperative Period

Identifiers

PMID31240434
OpenAlexW2953820688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.