ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2020
Heart rate variability is depressed in the early transitional period for newborns with complex congenital heart disease.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Preoperative Heart Rate Variability and Parasympathetic Modulation in Newborns with Transposition of the Great Arteries Undergoing Arterial Switch Operation.Children (Basel, Switzerland) · 2026Article
- Neonatal pre-discharge heart rate variability and neurodevelopmental outcomes at 1- and 5-years in children with transposition of the great arteries.Pediatric research · 2026Article
- Skin-to-skin contact significantly impacts maternal anxiety, mother-infant bonding, and autonomic function in infants with congenital heart disease and their mothers.Scientific reports · 2026Article
- Heart Rate Variability in Congenital Heart Disease and Controls Using Wearable Technology and a Health Application Programming Interface-A Cross-sectional Study.CJC pediatric and congenital heart disease · 2026Article
- Cardiac Autonomic Function and Atrial Arrhythmias in Adult Patients With a Univentricular Physiology After Fontan Palliation.CJC pediatric and congenital heart disease · 2026Article
- Preoperative autonomic failure in neonates with critical congenital heart disease.Early human development · 2025Article
- Decreased Heart Rate Variability in Children with Acute Decompensated Heart Failure is Associated with Poor Outcomes.Pediatric cardiology · 2024Article
- Machine Learning-Based Critical Congenital Heart Disease Screening Using Dual-Site Pulse Oximetry Measurements.Journal of the American Heart Association · 2024Article
- Contemporary Understanding of the Central Autonomic Nervous System in Fetal-Neonatal Transition.Seminars in pediatric neurology · 2023Article
- In infants with congenital heart disease autonomic dysfunction is associated with pre-operative brain injury.Pediatric research · 2022Article
- Autonomic development in preterm infants is associated with morbidity of prematurity.Pediatric research · 2022Article
- Stress and autonomic nerve dysfunction monitoring in perioperative gastric cancer patients using a smart device.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022Observational
- Neonatal heart rate variability: a contemporary scoping review of analysis methods and clinical applications.BMJ open · 2021Article
- Changes in Heart Rate and Heart Rate Variability During Surgical Stages to Completed Fontan Circulation.Pediatric cardiology · 2021Article
- Heart Rate Variability in the Perinatal Period: A Critical and Conceptual Review.Frontiers in neuroscience · 2020Review
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
purposeTo compare early changes in autonomic nervous system (ANS) tone between newborns with complex congenital heart disease (CHD) and newborns without CHD.
methodsWe performed a case-control study of heart rate variability (HRV) in newborns with complex CHD [transposition of the great arteries (TGA) or hypoplastic left heart syndrome (HLHS)] and low-risk control newborns without CHD. Cases with CHD were admitted following birth to a pediatric cardiac intensive care unit and had archived continuous ECG data. Control infants were prospectively enrolled at birth. ECG data in cases and controls were analyzed for HRV in the time and frequency domains at 24 h of age. We analyzed the following HRV metrics: alpha short (α
resultsHRV data from 57 infants with CHD (TGA, n = 33 and HLHS, n = 24) and from 29 controls were analyzed. The HRV metrics α
conclusionsInfants with complex CHD have depressed autonomic balance in the early postnatal period, which may complicate the fetal-neonatal transition.
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Registered trials
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