Evidence map›Paper›PMID 31240420›Full record

ReviewJournal of experimental orthopaedics2019

The biomechanical role of meniscal allograft transplantation and preliminary in-vivo kinematic evaluation.

Stefano Zaffagnini, Stefano Di Paolo, Federico Stefanelli, Giacomo Dal Fabbro, Luca Macchiarola, Gian Andrea Lucidi, Alberto Grassi

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of experimental orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05840887 (Knee Osteotomy Associated With Allograft Meniscus Transplantation in Patients With Altered Mechanical Axis, Meniscectomy Outcomes, and Osteoarthritis), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05840887 narecruitingnot on this mapstarted 2023, after this paper: background citation

Knee Osteotomy Associated With Allograft Meniscus Transplantation in Patients With Altered Mechanical Axis, Meniscectomy Outcomes, and Osteoarthritis: Clinical, Biomechanical, and Biological Evaluation

TypeinterventionalSponsorIstituto Ortopedico RizzoliRan2023 to 2026Enrolled52ConditionsMalalignment, Bone, Osteoarthritis, KneeArmsKnee osteotomy associated with meniscal allograft transplantation, Knee osteotomy
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Meniscus allograft transplantation for biologic knee preservation: gold standard or dilemma?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  9. Article
  10. Knee Joint Menisci Are Shock Absorbers: A BiomechanicalFrontiers in bioengineering and biotechnology · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Revision ACL Reconstruction: Principles and Practice.Indian journal of orthopaedics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefano ZaffagniniIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Stefano Di PaoloIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Federico StefanelliIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. federico.stefanelli@outlook.it.ORCID http://orcid.org/0000-0001-5545-3099
Giacomo Dal FabbroIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Luca MacchiarolaIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Gian Andrea LucidiIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Alberto GrassiIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeniscus allograft transplantation (MAT) is a surgical procedure performed in patients complaining post-meniscectomy syndrome. Although the effectiveness of MAT on knee stability has been already demonstrated in cadaveric studies, its biomechanical role has been poorly evaluated in-vivo.

methodsA narrative review of the biomechanical effect of meniscectomy and MAT was performed. Furthermore, two cases were presented, of one patient who underwent Medial MAT and Anterior Cruciate Ligament (ACL) reconstruction, and one who underwent Lateral MAT. During the surgery, knee laxity was evaluated using a surgical navigation system.

resultsAP laxity and IE rotation were reduced of 25% to 50% at both 30° and 90° of knee flexion after MAT transplantation. DISCUSSION: In both cases, almost all the tests performed showed a reduction of knee laxity after meniscus transplant, when compared with pre-operative knee laxity. This assessment confirms the insights of previous in-vitro studies and underline a crucial role of MAT in knee biomechanics.

Indexed as

Biomechanical evaluationKneeLaxity testMeniscusMeniscus allograft transplantation

Identifiers

PMID31240420
PMCPMC6593038

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.