Evidence map›Paper›PMID 31240362›Full record

ReviewInternational urogynecology journal2019

Small fiber polyneuropathy as a potential therapeutic target in interstitial cystitis/bladder pain syndrome.

Catherine A Matthews, Shaun P Deveshwar, Robert J Evans, Gopal Badlani, Stephen J Walker

Open access · greenAbstract readReview
In one paragraph

Review in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Understanding bladder pain syndrome/interstitial cystitis.International urogynecology journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Catherine A MatthewsDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
Shaun P DeveshwarWake Forest Institute for Regenerative Medicine, Wake Forest Baptist Medical Center, 391 Technology Way, Winston Salem, NC, 27101, USA.
Robert J EvansDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
Gopal BadlaniDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
Stephen J WalkerDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA. swalker@wakehealth.edu.ORCID http://orcid.org/0000-0002-0732-2366
Atrium Health Wake Forest Baptist · USForest Institute · US

Funding

Biomarkers for Molecular-Based Decision-Making in Diagnosis and Treatment of InteR21DK106554 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WALKER, STEPHEN · 2015 to 2016
$426k
NIDDK NIH HHS 5R21DK106554-02NIDDK NIH HHS R21 DK106554
6 · The paper itself

Abstract

introduction and hypothesisInterstitial cystitis/bladder pain syndrome (IC/BPS) and fibromyalgia (FM) are frequently co-occurring medical diagnoses in patients referred to the urology clinic for secondary and tertiary treatment options.

methodsAbundant literature has shown that many patients with FM have small fiber polyneuropathy (SFPN) that can be confirmed via skin punch biopsy and immunological staining to measure nerve density. RESULTS AND

conclusionsThis finding of SFPN provides a therapeutic target for FM and in this article we hypothesize and provide rationale for the idea that this same phenomenon (SFPN) might explain, in some IC/BPS patients, the finding of widespread pain and likewise provide a therapeutic target for these patients.

Indexed as

Cystitis, InterstitialFibromyalgiaHumansPolyneuropathiesFibromyalgiaInterstitial cystitis/bladder pain syndromePolyneuropathy

Identifiers

PMID31240362
PMCPMC7821096
OpenAlexW2954816961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.