Evidence map›Paper›PMID 31239865›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Analytical Method Validation of Gamijakyakgamchobuja-Tang (KCHO-1, Mecasin) Preparation.

Tingting Wang, Seongjin Lee, Muhack Yang, Eunhye Cha, Jongwon Jang, Sungchul Kim

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tingting WangDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.ORCID 0000-0001-6834-5900
Seongjin LeeDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.
Muhack YangDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.
Eunhye ChaDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.
Jongwon JangDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.
Sungchul KimDepartment of Acupuncture & Moxibustion Medicine, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju 61729, Republic of Korea.ORCID 0000-0001-9274-9243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have confirmed that KCHO-1 (Mecasin) was developed to alleviate the symptoms of Amyotrophic Lateral Sclerosis (ALS). And its toxicity test has also been carried out. The aim of this study is confirming the validation and stability of concentration analysis method of the Mecasin preparations using HPLC. As a conclusion, we found that the preparations at the concentrations of 50mg/ml and 200mg/ml in sterilized distilled water were homogeneous and it was stable for 4 hours at room temperature and 7 days refrigerated condition (2~8°C). And this method for analyzing the concentration of the Mecasin preparations has been found to be suitable. This study is helpful to promote development of reliable manufacturing medicine and good researches through definitive quality control of Mecasin as complex herbal medicine, aiming to provide help for the treatment of ALS.

Identifiers

PMID31239865
PMCPMC6556306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.