ReviewClinical and experimental gastroenterology2019
Eosinophilic gastroenteritis: diagnosis and clinical perspectives.
Review in Clinical and experimental gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed, 111 citations in OpenAlex.
- Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Trial
- Eosinophilic Duodenitis and Jejunitis with Ascites and Peripheral Eosinophilia: A Diagnostic Challenge-Case Report.Life (Basel, Switzerland) · 2026Article
- From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders.World journal of gastrointestinal pathophysiology · 2026Review
- Eosinophilic gastroenteritis in a 45-year-old female with epigastric abdominal pain: a rare case report.Annals of medicine and surgery (2012) · 2026Article
- Eosinophilic Gastroenteritis with Atopic Dermatitis: A Case Report and Literature Review.Journal of asthma and allergy · 2026Article
- Prevalence and patterns of Functional Gastrointestinal Disorders (FGIDs) among 18- to 69-year-old adults - A cross-sectional survey in Ernakulam District, Kerala, India.Journal of family medicine and primary care · 2025Article
- Eosinophilic Gastroenteritis Accompanied with Partial Midgut Malrotation in an Adult: A Case Report.The American journal of case reports · 2025Article
- Eosinophilic gastroenteritis with negative endoscopic biopsy and no peripheral eosinophilia: A case report.Medicine · 2025Article
- Chronic Eosinophilic Gastritis Presenting as Gastric Outlet Obstruction in a Young Man: A Case Report.The Korean journal of helicobacter and upper gastrointestinal research · 2025Article
- Eosinophilic gastroenteritis with severe gastrointestinal intolerance: A case report and literature review.The Journal of international medical research · 2025Review
- Age-Dependent Clinical Manifestations of Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis.Journal of asthma and allergy · 2025Article
- Tapeworm-Induced Eosinophilic Colitis: A Case Report.Case reports in gastrointestinal medicine · 2025Article
- A Patient With Eosinophilic Gastroenteritis Presenting With Severe Abdominal Pain.Clinical case reports · 2024Article
- The Unusual Clinical Presentation of Eosinophilic Gastroenteritis and Its Response to Mepolizumab: Two Case Reports.Cureus · 2024Article
- Eosinophilic Duodenitis Presenting As Severe Iron Deficiency Anemia: A Rare Presentation.Cureus · 2024Article
- Article
- Eosinophilic ascites and enteritis: a neglected case report from Vietnam.The Journal of international medical research · 2024Article
- Review
- Eosinophilic gastritis and gluten-sensitive enteropathy manifested as hypoproteinemia and treated with omalizumab: a case report.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024Article
- Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eosinophilic gastroenteritis (EGE) is a digestive disorder in children and adults that is characterized by eosinophilic infiltration in the stomach and intestine. The underlying molecular mechanisms predisposing to this disease are unknown, but it seems that hypersensitivity response plays a major role in its pathogenesis, as many patients have a history of seasonal allergies, food sensitivities, asthma, and eczema. Symptoms and clinical presentations vary, depending on the site and layer of the gastrointestinal wall infiltrated by eosinophils. Laboratory results, radiological findings, and endoscopy can provide important diagnostic evidence for EGE; however, the cornerstone of the diagnosis remains the histological examination of gastric and duodenal specimens for evidence of eosinophilic infiltration (>20 eosinophils per high-power field), and finally clinicians make the diagnosis in correlation with and by exclusion of other disorders associated with eosinophilic infiltration. Although spontaneous remission is reported in around 30%-40% of EGE cases, most patients require ongoing treatment. The management options for this disorder include both dietary and pharmacological approaches, with corticosteroids being the mainstay of therapy and highly effective. The subsequent course is quite variable. Some patients have no recurrences, while a few experience recurrent symptoms during or immediately after corticosteroid interruption. An alternative therapeutic armamentarium includes mast-cell stabilizers, leukotriene antagonists, antihistamines, immunomodulators, and biological agents. In this review, we provide a summary of the different diagnostic tools utilized in practice, as well as the different therapeutic approaches available for EGE management.
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