Evidence map›Paper›PMID 31239676›Full record

ArticleInternational journal of nanomedicine2019

Dexamethasone-loaded injectable silk-polyethylene glycol hydrogel alleviates cisplatin-induced ototoxicity.

Yuming Chen, Jiayi Gu, Jian Liu, Ling Tong, Fuxin Shi, Xiaoqin Wang, Xueling Wang, Dehong Yu, Hao Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  12. A Pt(IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
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  15. Article
  16. Article
  17. The Use of Nanoparticles in Otoprotection.Frontiers in neurology · 2022
    Review
  18. [Development of novel drug carrier via round window membrane].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Review
  19. Disruption ofFrontiers in cellular neuroscience · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yuming ChenDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Jiayi GuDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Jian LiuNational Engineering Laboratory for Modern Silk, Soochow University , Suzhou 215123, People's Republic of China.
Ling TongDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Fuxin ShiDepartment of Otology and Laryngology, Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Decibel Therapeutics , Boston, MA, 02215, USA.
Xiaoqin WangNational Engineering Laboratory for Modern Silk, Soochow University , Suzhou 215123, People's Republic of China.
Xueling WangDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Dehong YuDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Hao WuDepartment of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, People's Republic of China.
Shanghai Jiao Tong University · CNMassachusetts Eye and Ear Infirmary · USShanghai Ninth People's Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

InjectionsAnimalsBiocompatible MaterialsBombyxCell LineCisplatinCochleaDexamethasoneDisease Models, AnimalDrug LiberationEarGuinea PigsHearing LossHydrogelsMice, Inbred C57BLPolyethylene GlycolsBiocompatible MaterialsCisplatinDexamethasoneHydrogelsPolyethylene GlycolsProtective AgentsReactive Oxygen SpeciesSilkcisplatin-induced hearing lossdexamethasoneround window membranesilk-polyethyleneglycol hydrogel

Identifiers

PMID31239676
PMCPMC6559256
OpenAlexW2948721358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.