Evidence map›Paper›PMID 31239658›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2019

High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study.

Jiayan Sun, Yujie Li, Bingyu Ling, Qingcheng Zhu, Yingying Hu, Dingyu Tan, Ping Geng, Jun Xu

Erratum issuedOpen access · goldAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 7 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 7 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  10. Hospital Cost Savings for Sequential COPD Patients Receiving Domiciliary Nasal High Flow Therapy.International journal of chronic obstructive pulmonary disease · 2022
    Trial
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  15. Short-acting βInternal medicine (Tokyo, Japan) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jiayan SunDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Yujie LiDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Bingyu LingDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Qingcheng ZhuDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Yingying HuDepartment of Emergency, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Dingyu TanDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Ping GengDepartment of Emergency, Clinical Medical College, Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Jun XuDepartment of Emergency, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, People's Republic of China.
Yangzhou University · CNNorthern Jiangsu People's Hospital · CNFirst Affiliated Hospital of Henan University of Science and Technology · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High-flow nasal cannula (HFNC) oxygen therapy in acute hypoxic respiratory failure is becoming increasingly popular. However, evidence to support the use of HFNC in acute respiratory failure (ARF) with hypercapnia is limited. Methods: Chronic obstructive pulmonary disease (COPD) patients with moderate hypercapnic ARF (arterial blood gas pH 7.25-7.35, PaCO Results: Eighty-two COPD patients (39 in the HFNC group and 43 in the NIV group) were enrolled in this study. The mean age was 71.8±8.2 and 54 patients (65.9%) were male. The treatment failed in 11 out of 39 patients with HFNC (28.2%) and in 17 of 43 patients with NIV (39.5%) ( Conclusion: Among COPD patients with moderate hypercarbic ARF, the use of HFNC compared with NIV did not result in increased rates of treatment failure, while there were fewer nursing interventions and skin breakdown episodes reported in the HFNC group.

Indexed as

CannulaNoninvasive VentilationAdministration, IntranasalAgedAged, 80 and overFemaleHumansHypercapniaLungMaleMiddle AgedOxygen Inhalation TherapyPulmonary Disease, Chronic ObstructiveRespiratory InsufficiencyRetrospective StudiesRisk Factorschronic obstructive pulmonary diseasescohort studyhigh-flow nasal cannulanon-invasive ventilationrespiratory failure

Identifiers

PMID31239658
PMCPMC6556470
OpenAlexW2948064614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.