Evidence map›Paper›PMID 31239489›Full record

ArticleScientific reports2019

Relevant Word Order Vectorization for Improved Natural Language Processing in Electronic Health Records.

Jeffrey Thompson, Jinxiang Hu, Dinesh Pal Mudaranthakam, David Streeter, Lisa Neums, Michele Park, Devin C Koestler, Byron Gajewski, Roy Jensen, Matthew S Mayo

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeffrey ThompsonDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA. jthompson21@kumc.edu.
Jinxiang HuDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Dinesh Pal MudaranthakamDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
David StreeterDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Lisa NeumsDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Michele ParkUniversity of Kansas Cancer Center, Kansas City, KS, USA.
Devin C KoestlerDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Byron GajewskiDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.
Roy JensenUniversity of Kansas Cancer Center, Kansas City, KS, USA.ORCID http://orcid.org/0000-0003-4430-2281
Matthew S MayoDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NICOLE L NOLLEN · 2012 to 2026
$40.1M
Using Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ANDREW K. GODWIN · 2019 to 2026
$21.5M
NCI NIH HHS P30 CA168524NIGMS NIH HHS P20 GM130423
6 · The paper itself

Abstract

Electronic health records (EHR) represent a rich resource for conducting observational studies, supporting clinical trials, and more. However, much of the data contains unstructured text, presenting an obstacle to automated extraction. Natural language processing (NLP) can structure and learn from text, but NLP algorithms were not designed for the unique characteristics of EHR. Here, we propose Relevant Word Order Vectorization (RWOV) to aid with structuring. RWOV is based on finding the positional relationship between the most relevant words to predicting the class of a text. This facilitates machine learning algorithms to use the interaction of not just keywords but positional dependencies (e.g. a relevant word occurs 5 relevant words before some term of interest). As a proof-of-concept, we attempted to classify the hormone receptor status of breast cancer patients treated at the University of Kansas Medical Center, comparing RWOV to other methods using the F1 score and AUC. RWOV performed as well as, or better than other methods in all but one case. For F1 score, RWOV had a clear edge on most tasks. AUC tended to be closer, but for HER2, RWOV was significantly better for most comparisons. These results suggest RWOV should be further developed for EHR-related NLP.

Indexed as

AlgorithmsMachine LearningNatural Language ProcessingBreast NeoplasmsDatasets as TopicElectronic Health RecordsErb-b2 Receptor Tyrosine KinasesFemaleHumansReceptors, EstrogenReceptors, ProgesteroneERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID31239489
PMCPMC6592944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.