Evidence map›Paper›PMID 31239444›Full record

ArticleNature communications2019

m

Seungwon Yang, Jiangbo Wei, Yan-Hong Cui, Gayoung Park, Palak Shah, Yu Deng, Andrew E Aplin, Zhike Lu, Seungmin Hwang, Chuan He and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 480 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
480citing papers in PubMed, 1 pooled it
39.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

480 citing papers in PubMed, 1 synthesis or guideline pooled it, 810 citations in OpenAlex.

  1. Global research trends in mFrontiers in genetics · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. mClinical and translational medicine · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. cGAMP suppresses FTO expression to promote mCellular and molecular life sciences : CMLS · 2026
    Article
  11. Review
  12. RNA modifications and cancer ferroptosis.Cancer cell international · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  17. Review
  18. NNature reviews. Cancer · 2026
    Review
  19. Article
  20. Review

420 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Seungwon YangDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, 60637, USA.ORCID http://orcid.org/0000-0002-8970-7373
Jiangbo WeiDepartments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 60637, USA.
Yan-Hong CuiDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, 60637, USA.
Gayoung ParkDepartment of Pathology, University of Chicago, Chicago, IL, 60637, USA.
Palak ShahDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, 60637, USA.ORCID http://orcid.org/0000-0002-6142-5630
Yu DengDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, 60637, USA.ORCID http://orcid.org/0000-0003-2292-2957
Andrew E AplinDepartment of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.ORCID http://orcid.org/0000-0002-2734-3244
Zhike LuDepartments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 60637, USA.
Seungmin HwangDepartment of Pathology, University of Chicago, Chicago, IL, 60637, USA.ORCID http://orcid.org/0000-0003-0846-5462
Chuan HeDepartments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 60637, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424
Yu-Ying HeDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, 60637, USA. yyhe@medicine.bsd.uchicago.edu.ORCID http://orcid.org/0000-0002-2665-7962
University of Chicago · USHoward Hughes Medical Institute · USThomas Jefferson University · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
YTHDF2 and UVB damage response in skin cancerR01ES024373 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2015 to 2023
$4.3M
The mechanistic role of METTL14 in UVB-induced skin tumorigenesisR01ES030576 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2019 to 2023
$3.0M
Direct Oxidative Nucleic Acids DemethylationR01ES030546 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2019 to 2023
$1.9M
Mutant BRAF-regulated transcription factors in melanoma progressionR01CA196278 · NCI · THOMAS JEFFERSON UNIVERSITY · PI APLIN, ANDREW ERIC · 2015 to 2019
$1.8M
Targeting by autophagy proteins for anti-tumor immunityDP2CA225208 · NCI · UNIVERSITY OF CHICAGO · PI HWANG, SEUNGMIN · 2017 to 2017
$510k
NCATS NIH HHS UL1 TR000430NCI NIH HHS DP2 CA225208NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA196278NIEHS NIH HHS P30 ES027792NIEHS NIH HHS R01 ES024373NIEHS NIH HHS R01 ES030546NIEHS NIH HHS R01 ES030576
6 · The paper itself

Abstract

Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N

Indexed as

AdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedCarcinogenesisCell Line, TumorCell ProliferationDemethylationDNA MethylationFemaleHumansImmunotherapyMelanomaMiceMice, Inbred C57BLAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedatezolizumabFTO protein, humanFTO protein, mouseN-methyladenosineProgrammed Cell Death 1 ReceptorRNA, Messenger

Identifiers

PMID31239444
PMCPMC6592937
OpenAlexW2953467762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.