Evidence map›Paper›PMID 31239353›Full record

ArticleThe Journal of biological chemistry2019

Zinc-dependent activation of the Pho8 alkaline phosphatase in

Ya-Mei Hu, Derek M Boehm, Hak Chung, Stevin Wilson, Amanda J Bird

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Vacuolar Proteases ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Zinc homeostasis in Schizosaccharomyces pombe.Archives of microbiology · 2023
    Review
  5. Article
  6. Zinc homeostasis in the secretory pathway in yeast.Current opinion in chemical biology · 2020
    Review
  7. Transcription factors and transporters in zinc homeostasis: lessons learned from fungi.Critical reviews in biochemistry and molecular biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ya-Mei HuDepartment of Human Nutrition, Ohio State University, Columbus, Ohio 43210.
Derek M BoehmDepartment of Molecular Genetics, Ohio State University, Columbus, Ohio 43210.
Hak ChungOhio State University Interdisciplinary Nutrition Program, Ohio State University, Columbus, Ohio 43210.
Stevin WilsonDepartment of Molecular Genetics, Ohio State University, Columbus, Ohio 43210.
Amanda J BirdDepartment of Human Nutrition, Ohio State University, Columbus, Ohio 43210; Department of Molecular Genetics, Ohio State University, Columbus, Ohio 43210; Center for RNA Biology, Ohio State University, Columbus, Ohio 43210. Electronic address: bird.96@osu.edu.
The Ohio State University · US

Funding

Zinc-dependent regulation of gene expressionR01GM105695 · NIGMS · OHIO STATE UNIVERSITY · PI BIRD, AMANDA JANE · 2014 to 2018
$1.4M
Typhoon FLA9500 Biomedical ImagerS10OD023582 · OD · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH · 2017 to 2017
$144k
NIGMS NIH HHS R01 GM105695NIH HHS S10 OD023582
6 · The paper itself

Abstract

Genome-wide analyses have revealed that during metal ion starvation, many cells undergo programmed changes in their transcriptome or proteome that lower the levels of abundant metalloproteins, conserving metal ions for more critical functions. Here we investigated how changes in cellular zinc status affect the expression and activity of the zinc-requiring Pho8 alkaline phosphatase from fission yeast (

Indexed as

Alkaline PhosphataseEnzyme ActivationRNA, FungalRNA, MessengerSchizosaccharomycesSchizosaccharomyces pombe ProteinsZincAlkaline PhosphataseRNA, FungalRNA, MessengerSchizosaccharomyces pombe ProteinsZinccation diffusion facilitatorgene expressionhypophosphatemiametal homeostasisprotein processingprotein stabilitytransition metaltransport metalyeast geneticszinc transport

Identifiers

PMID31239353
PMCPMC6699849
OpenAlexW2953852746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.