Evidence map›Paper›PMID 31239344›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of

Jinhui Tao, Yongsoon Shin, Rajith Jayasinha, Garry W Buchko, Sarah D Burton, Alice C Dohnalkova, Zheming Wang, Wendy J Shaw, Barbara J Tarasevich

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  10. Amyloid-like amelogenin nanoribbons template mineralization via a low-energy interface of ion binding sites.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jinhui TaoPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Yongsoon ShinPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Rajith JayasinhaPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Garry W BuchkoPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.ORCID 0000-0002-3639-1061
Sarah D BurtonPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Alice C DohnalkovaPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Zheming WangPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Wendy J ShawPhysical and Computational Sciences, Pacific Northwest National Laboratory, Richland, WA 99354.
Barbara J TarasevichEnergy and Environment, Pacific Northwest National Laboratory, Richland, WA 99354 barbara.tarasevich@pnnl.gov.ORCID 0000-0001-9444-6836
Pacific Northwest National Laboratory · US

Funding

Structural, spatial, and temporal features guiding amelogenins transformation of calcium phosphate into enamelR01DE015347 · NIDCR · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SHAW, WENDY J · 2005 to 2025
$8.2M
NIDCR NIH HHS R01 DE015347
6 · The paper itself

Abstract

Small variations in the primary amino acid sequence of extracellular matrix proteins can have profound effects on the biomineralization of hard tissues. For example, a change in one amino acid within the amelogenin protein can lead to drastic changes in enamel phenotype, resulting in

Indexed as

AdsorptionAmelogenesis ImperfectaAmelogeninAmino AcidsAmino Acid SequenceAmino Acid SubstitutionAnimalsBiomineralizationDurapatiteEnergy MetabolismExtracellular Matrix ProteinsHumansMatrix Metalloproteinase 20MiceMicroscopy, Atomic ForceProtein ConformationAmelogeninAmino AcidsDurapatiteExtracellular Matrix ProteinsMatrix Metalloproteinase 20Mmp20 protein, mouseamelogeninbiomineralizationprotein adsorption

Identifiers

PMID31239344
PMCPMC6628643
OpenAlexW2955828730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.