Evidence map›Paper›PMID 31239147›Full record

ArticleProgress in brain research2019

Non-commutative, nonlinear, and non-analytic aspects of the ocular motor plant.

Joseph L Demer

Abstract read
In one paragraph

Article in Progress in brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Joseph L DemerStein Eye Institute and Departments of Ophthalmology and Neurology, University of California, Los Angeles, CA, United States. Electronic address: jld@jsei.ucla.edu.

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313
6 · The paper itself

Abstract

The ocular motor plant, consisting of the globe, extraocular muscles (EOMs), and connective tissue suspension, constitutes an intricate and non-linear actuator of eye movements. The pulley system of the rectus EOMs constitutes a non-linear inner gimbal actuated by the orbital layers of these EOMs that renders the sequence of ocular rotations effectively commutative to the central controller, and can be rotated by the outer gimbal driven by the oblique EOMs. Optic nerve (ON) length is insufficient to permit large angle adduction without tethering by the ON and sheath, creating at and beyond this threshold a large additional load on the medial rectus muscle. Finite element modeling suggests that adduction may eventually cause repetitive strain injury to the ON and glaucomatous optic nerve damage.

Indexed as

Finite Element AnalysisModels, TheoreticalAnimalsEye MovementsGlaucomaHumansOculomotor MusclesOptic NerveCommutativityFinite element analysisGlaucomaOptic nervePulley

Identifiers

PMID31239147
PMCPMC7384247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.