Evidence map›Paper›PMID 31238930›Full record

ArticleBMC complementary and alternative medicine2019

Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts.

Bartosz Skalski, Bogdan Kontek, Bernadetta Lis, Beata Olas, Łukasz Grabarczyk, Anna Stochmal, Jerzy Żuchowski

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Beneficial effects ofPharmaceutical biology · 2025
    Review
  2. Article
  3. Isorhamnetin: what is theFrontiers in pharmacology · 2024
    Review
  4. Phytochemistry and pharmacology of sea buckthorn (Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023
    Review
  5. Review
  6. Review
  7. Article
  8. LC/MS Analysis of Saponin Fraction from the Leaves ofMolecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bartosz SkalskiDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/3, 90-236, Łódź, Poland.
Bogdan KontekDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/3, 90-236, Łódź, Poland.
Bernadetta LisDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/3, 90-236, Łódź, Poland.
Beata OlasDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/3, 90-236, Łódź, Poland. beata.olas@biol.uni.lodz.pl.
Łukasz GrabarczykDepartment of Neurology and Neurosurgery, Faculty of Medical Sciences, University of Warmia and Mazury, Warszawska 30, 10-082, Olsztyn, Poland.
Anna StochmalDepartment of Biochemistry, Institute of Soil Science and Plant Cultivation, State Research Institute, Czartoryskich 8, 24-100, Puławy, Poland.
Jerzy ŻuchowskiDepartment of Biochemistry, Institute of Soil Science and Plant Cultivation, State Research Institute, Czartoryskich 8, 24-100, Puławy, Poland.
University of Łódź · PLInstitute of Soil Science and Plant Cultivation · PLUniversity of Warmia and Mazury in Olsztyn · PL

Funding

Narodowe Centrum Nauki 2015/19/B/NZ9/03164
6 · The paper itself

Abstract

backgroundSea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of this plant (both fresh and dried) contain a lot of nutrients and bioactive compounds, including phenolic compounds. The present study was carried out in order to investigate antioxidant and anticoagulant properties of sea buckthorn twig and leaf extracts (0.5-50 μg/mL) by using various in vitro models. Moreover, the aim of present experiments was to compare the biological activity of SBT leaf extract and SBT twig extract with selected berry extracts (a rich source of phenolic compounds): SBT berry extract (flavonoids being the dominant components), a commercial extract from the berries of Aronia melanocarpa (Aronox®), and a grape seed extract.

methodsWe determined the effect of plant extracts on the oxidative stress using selected markers of this process, i.e. the level of carbonyl groups in proteins. Additionally, we analysed the potential mechanism of modulation of hemostatic properties of human plasma (using selected coagulation times).

resultsSBT twig and leaf extracts were observed to exhibit an antioxidant activity against two strong biological oxidants: hydrogen peroxide (H

conclusionsOur present results have demonstrated that extracts from different parts of SBT, especially berries and twigs, in comparison to well-known berries (aronia and grape), may also be viewed as a good source of active substances - antioxidants for pharmacological or cosmetic applications. Moreover, it is very important from an economic point of view to know that there is a possibility of obtaining phenolic compounds not only from the berries or leaves, but also from twigs, which constitute a production waste.

Indexed as

AnticoagulantsAntioxidantsElaeagnaceaeFlavonoidsFruitHumansPhenolsPhotiniaPlant ExtractsPlant LeavesPlant StemsProthrombin TimeAnticoagulantsAntioxidantsFlavonoidsPhenolsPlant ExtractsBerryElaeagnus rhamnoides (L.) a. NelsonHemostasisLeafOxidative stressPhenolic compoundsTwig

Identifiers

PMID31238930
PMCPMC6591864
OpenAlexW2953719507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.