Evidence map›Paper›PMID 31238890›Full record

SynthesisBMC medical genetics2019

Relationship between TGF-β1 + 869 T/C and + 915 G/C gene polymorphism and risk of acute rejection in renal transplantation recipients.

Hong-Yan Li, Tianbiao Zhou, Shujun Lin, Wenshan Lin

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in BMC medical genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hong-Yan LiDepartment of Nephrology, Huadu District People's Hospital of Guangzhou, Huadu Hospital of Southern Medical University, 510800, No 22 Baohua Road, Guangzhou, China.
Tianbiao ZhouDepartment of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. zhoutb@aliyun.com.
Shujun LinDepartment of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Wenshan LinDepartment of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.ORCID 0000-0002-3485-1896
Shantou University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis meta-analysis was conducted to assess the relationship between the transforming growth factor-beta 1 (TGF-β1) + 869 T/C gene polymorphism, + 915 G/C gene polymorphism, and the susceptibility of acute rejection in the recipients with renal transplantation.

methodsRelevant studies were searched and identified from the Cochrane Library and PubMed, and eligible investigations were recruited and data were calculated by meta-analysis.

resultsIn this study, we found no relationship between either TGF-β1 + 869 T/C or TGF-β1 + 915 G/C gene polymorphism and acute rejection susceptibility in patients with renal transplantation. No association between either gene polymorphism and acute rejection susceptibility in patients with renal transplantation in Caucasian, Asian, or African populations individually was found.

conclusionThe TGF-β1 + 869 T/C and + 915 G/C gene polymorphisms are not associated with acute rejection susceptibility in recipients with renal transplantation.

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseGraft RejectionKidney TransplantationPolymorphism, Single NucleotideAsian PeopleDatabases, FactualGenotypeHumansOdds RatioTransforming Growth Factor beta1White PeopleTransforming Growth Factor beta1Acute rejectionMeta-analysisPolymorphismsRenal transplantationTGF-β1

Identifiers

PMID31238890
PMCPMC6593503
OpenAlexW2955870076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.