ArticleMicroorganisms2019
Survey of Biosynthetic Gene Clusters from Sequenced Myxobacteria Reveals Unexplored Biosynthetic Potential.
Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Predator avoidance promotes inter-bacterial symbiosis with myxobacteria in polymicrobial communities.bioRxiv : the preprint server for biology · 2026Article
- Establishing conserved biosynthetic gene clusters of the phylum Myxococcota.Applied and environmental microbiology · 2026Article
- Predator avoidance promotes interbacterial symbiosis with myxobacteria in polymicrobial communities.The ISME journal · 2026Article
- Anticancer Compounds from Myxobacteria: Current Scenario and Future Perspectives.Anti-cancer agents in medicinal chemistry · 2026Review
- Comparative Genomic Analysis ofMicroorganisms · 2025Article
- Jejupeptins A and B, Polyketide-Cyclic Peptide Hybrids with Anti-Corticosterone Activity fromACS omega · 2025Article
- MyxoPortal: a database of myxobacterial genomic features.Database : the journal of biological databases and curation · 2024Article
- Bivariate One Strain Many Compounds Designs Expand the Secondary Metabolite Production Space inMicroorganisms · 2023Article
- Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata.MicrobiologyOpen · 2023Article
- The Pangenome of Gram-Negative Environmental Bacteria Hides a Promising Biotechnological Potential.Microorganisms · 2023Article
- Phylogenetic Revisit to a Review on Predatory Bacteria.Microorganisms · 2023Review
- Biosynthetic Potential ofJournal of fungi (Basel, Switzerland) · 2023Article
- Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp.Microbial biotechnology · 2023Article
- In Silico and In Vitro Analyses Reveal Promising Antimicrobial Peptides from Myxobacteria.Probiotics and antimicrobial proteins · 2023Article
- Article
- Sandacrabins - Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Unveiling the genomic potential ofMicrobial genomics · 2022Article
- Concepts and conjectures concerning predatory performance of myxobacteria.Frontiers in microbiology · 2022Review
- Myxobacterial Genomics and Post-Genomics: A Review of Genome Biology, Genome Sequences and Related 'Omics Studies.Microorganisms · 2021Review
- Assessment of Evolutionary Relationships for Prioritization of Myxobacteria for Natural Product Discovery.Microorganisms · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Coinciding with the increase in sequenced bacteria, mining of bacterial genomes for biosynthetic gene clusters (BGCs) has become a critical component of natural product discovery. The order Myxococcales, a reputable source of biologically active secondary metabolites, spans three suborders which all include natural product producing representatives. Utilizing the BiG-SCAPE-CORASON platform to generate a sequence similarity network that contains 994 BGCs from 36 sequenced myxobacteria deposited in the antiSMASH database, a total of 843 BGCs with lower than 75% similarity scores to characterized clusters within the MIBiG database are presented. This survey provides the biosynthetic diversity of these BGCs and an assessment of the predicted chemical space yet to be discovered. Considering the mere snapshot of myxobacteria included in this analysis, these untapped BGCs exemplify the potential for natural product discovery from myxobacteria.
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Registered trials
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