Evidence map›Paper›PMID 31238406›Full record

Observational studyIndian journal of ophthalmology2019

Causative fungi and treatment outcome of dematiaceous fungal keratitis in North India.

Ajit Kumar, Ashi Khurana, Mohit Sharma, Lokesh Chauhan

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Microbial Keratitis in Southern Arizona.Ophthalmic research · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Clinical profile and treatment outcomes ofIndian journal of ophthalmology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Mycotic Keratitis-A Global Threat from the Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2021
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ajit KumarDepartment of Cornea and Refractive Error, C L Gupta Eye Institute, Ram Ganga Vihar, Phase 2(Ext) Moradabad, Uttar Pradesh, India.
Ashi KhuranaDepartment of Cornea and Refractive Error, C L Gupta Eye Institute, Ram Ganga Vihar, Phase 2(Ext) Moradabad, Uttar Pradesh, India.
Mohit SharmaDepartment of Microbiology, C L Gupta Eye Institute, Ram Ganga Vihar, Phase 2(Ext) Moradabad, Uttar Pradesh, India.
Lokesh ChauhanDepartment of Clinical Research, C L Gupta Eye Institute, Ram Ganga Vihar, Phase 2(Ext) Moradabad, Uttar Pradesh, India.
IFTM University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of the study is to identify risk factors, clinical characteristics, causative fungi, and treatment outcome of dematiaceous fungal keratitis in North India. Methods: Consecutive cases of culture-proven dematiaceous fungal keratitis between January 2012 and June 2017 were retrieved from the medical record department. Risk factors, clinical signs, and outcome were registered. Results: Eighty-three patients were included. Identified dematiaceous fungal organism were Curvularia sp. (n = 55/83; 66.3%), Alternaria sp. (n = 12/83; 14.5%), Ulocladium sp. (n = 5/83; 6%), Bipolaris sp. (n = 5/83; 6.1%), Scedosporium sp. (n = 3/83; 3.6%), Acremonium sp. (n = 2/83; 2.4%), and Epicoccum sp. (n = 1/83; 1.2%). Male preponderance was reported. The most common predisposing factor was corneal trauma (67.4%). In cases associated with corneal trauma due to vegetative matter, sugarcane was the most common cause. In all, 89% of the patients were more than 30 years of age. The median infiltrate size was 8 mm Conclusion: Curvularia sp. and Alternaria sp. were the predominant pathogenic genera causing dematiaceous fungal keratitis. Among the causative fungi, infections due to Scedosporium sp. were associated with the worst outcomes. Ulocladium sp. and Epicoccum sp. were also identified. Both the species are not reported previously as a causal organism of dematiaceous fungal keratitis from North India.

Indexed as

AdultCorneaEye Infections, FungalFemaleFollow-Up StudiesHumansIncidenceIndiaKeratitisMaleMiddle AgedMitosporic FungiMycosesRetrospective StudiesRisk FactorsSlit LampAlternariaCurvulariadematiaceous fungiEpicoccumkeratitisUlocladiumUttar Pradesh

Identifiers

PMID31238406
PMCPMC6611278
OpenAlexW2954759182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.