Evidence map›Paper›PMID 31238286›Full record

ArticleSocial science & medicine (1982)2019

Managing uncertainty in medicine quality in Ghana: The cognitive and affective basis of trust in a high-risk, low-regulation context.

Heather Hamill, Kate Hampshire, Simon Mariwah, Daniel Amoako-Sakyi, Abigail Kyei, Michele Castelli

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  4. Article
  5. Transnational Criminal Enterprise: a Qualitative Social Network Analysis of the Production and Trade in Falsified Medicines.Archives europeennes de sociologie. European journal of sociology. Europaisches Archiv fur Soziologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heather HamillDepartment of Sociology, Oxford University, 42-43 Park End Street, Oxford, OX1 1JD, UK. Electronic address: heather.hamill@sociology.ox.ac.uk.
Kate HampshireDepartment of Anthropology, Durham University, Dawson Building, South Road, Durham, DH1 3LE, UK. Electronic address: k.r.hampshire@durham.ac.uk.
Simon MariwahDepartment of Geography and Regional Planning, University of Cape Coast, Cape Coast, Ghana. Electronic address: Simon.mariwah@gmail.com.
Daniel Amoako-SakyiMedical School, University of Cape Coast, Cape Coast, Ghana. Electronic address: dasakyi@yahoo.com.
Abigail KyeiThe Ghana College of Nurses and Midwives, Pentecost University, Accra, Ghana. Electronic address: abbie_office@yahoo.com.
Michele CastelliInstitute of Health and Society, Newcastle University The Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK. Electronic address: michele.castelli@newcastle.ac.uk.

Funding

Wellcome TrustWellcome Trust 110084/Z/15/Z
6 · The paper itself

Abstract

Where regulation is weak, medicine transactions can be characterised by uncertainty over the drug quality and efficacy, with buyers shouldering the greater burden of risk in exchanges that are typically asymmetric. Drawing on in-depth interviews (N = 220) and observations of medicine transactions, plus interviews with regulators (N = 20), we explore how people in Ghana negotiate this uncertainty and come to trust a medicine enough to purchase or ingest it. We identify two mechanisms - attempts to mitigate uncertainty through seeking observable signs of quality and attempts to reduce informational asymmetry - that underpin cognitive assessments of a medicine's trustworthiness. However, these 'cognitive' forms of trust assessment have limited traction where uncertainty is high and trustworthiness remains unknowable, so a third mechanism comes into play: one based on affective relationships within which transactions are socially embedded. Even these, however, cannot eliminate uncertainty, because of the dispersed and under-regulated nature of wider supply chains. In conclusion, we reflect on the need for careful research on actors' practices and decision-making across supply chains to inform more effective policy and regulation.

Indexed as

UncertaintyAdultCommerceFemaleGhanaHumansMaleObservationPharmaceutical PreparationsQualitative ResearchRisk AssessmentSocial Control, FormalTrustYoung AdultPharmaceutical PreparationsEthnographyGhanaMedicine qualityMedicine supply chainsRiskTrustUncertainty

Identifiers

PMID31238286
PMCPMC6688066

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.