ArticleJournal of biomedical informatics2019
HemOnc: A new standard vocabulary for chemotherapy regimen representation in the OMOP common data model.
Article in Journal of biomedical informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Common data models and data standards for tabular health data: a systematic review.BMC medical informatics and decision making · 2025Pooled it
- OMOP CDM Can Facilitate Data-Driven Studies for Cancer Prediction: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Application of Artificial Intelligence Methods to Pharmacy Data for Cancer Surveillance and Epidemiology Research: A Systematic Review.JCO clinical cancer informatics · 2020Pooled it
- Sieving for gold: external comparator studies to prioritize drugs for late-stage clinical trial.Journal of comparative effectiveness research · 2026Review
- AI driven hybrid convolutional and transformer based deep learning architecture for precise lung nodule classification.Scientific reports · 2026Article
- Completeness of Common Data Elements for Breast Cancer Clinical Trials in Observational Databases.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Design specifications for biomedical virtual twins in engineered adoptive cellular immunotherapies.NPJ digital medicine · 2025Review
- A scoping review of OMOP CDM adoption for cancer research using real world data.NPJ digital medicine · 2025Article
- Leveraging Large Language Models for Real-World Data Evidence: A Framework for Automated Treatment Extraction and Data Harmonization.Journal of registry management · 2025Article
- Phenotyping Hepatic Immune-Related Adverse Events in the Setting of Immune Checkpoint Inhibitor Therapy.JCO clinical cancer informatics · 2024Article
- DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms.Nucleic acids research · 2024Article
- Developing RxNorm Extension: A Step Toward Global Drug Data Harmonization in Observational Drug Research.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
- SEETrials: Leveraging large language models for safety and efficacy extraction in oncology clinical trials.Informatics in medicine unlocked · 2024Article
- Normalization of drug and therapeutic concepts with Thera-Py.JAMIA open · 2023Article
- LeafAI: query generator for clinical cohort discovery rivaling a human programmer.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Alcohol Consumption Among Adults With a Cancer Diagnosis in the All of Us Research Program.JAMA network open · 2023Article
- Clinical Informatics Approaches to Facilitate Cancer Data Sharing.Yearbook of medical informatics · 2023Review
- Pilot study of a European oncology regimen reference library and matching algorithm.European journal of hospital pharmacy : science and practice · 2023Article
- Standardized Description of the Feature Extraction Process to Transform Raw Data Into Meaningful Information for Enhancing Data Reuse: Consensus Study.JMIR medical informatics · 2022Article
- Patients Recently Treated for B-lymphoid Malignancies Show Increased Risk of Severe COVID-19.Blood cancer discovery · 2022Article
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9 authors.
Funding
Abstract
Systematic application of observational data to the understanding of impacts of cancer treatments requires detailed information models allowing meaningful comparisons between treatment regimens. Unfortunately, details of systemic therapies are scarce in registries and data warehouses, primarily due to the complex nature of the protocols and a lack of standardization. Since 2011, we have been creating a curated and semi-structured website of chemotherapy regimens, HemOnc.org. In coordination with the Observational Health Data Sciences and Informatics (OHDSI) Oncology Subgroup, we have transformed a substantial subset of this content into the OMOP common data model, with bindings to multiple external vocabularies, e.g., RxNorm and the National Cancer Institute Thesaurus. Currently, there are >73,000 concepts and >177,000 relationships in the full vocabulary. Content related to the definition and composition of chemotherapy regimens has been released within the ATHENA tool (athena.ohdsi.org) for widespread utilization by the OHDSI membership. Here, we describe the rationale, data model, and initial contents of the HemOnc vocabulary along with several use cases for which it may be valuable.
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