Evidence map›Paper›PMID 31237948›Full record

Trial reportJournal of the Pediatric Infectious Diseases Society2020

Effect of Concomitant Antibiotic and Vaccine Administration on Serologic Responses to Rotavirus Vaccine.

Evan J Anderson, Benjamin Lopman, Jumi Yi, Romina Libster, C Buddy Creech, Jill El-Khorazaty, Shahida Baqar, Inci Yildirim, Carol Kao, Nadine Rouphael and 2 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the Pediatric Infectious Diseases Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Evan J AndersonDepartments of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Benjamin LopmanRollins School of Public Health, Emory University, Atlanta, Georgia.
Jumi YiDepartments of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Romina LibsterDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
C Buddy CreechDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Jill El-KhorazatyEmmes Corporation, Rockville, Maryland.
Shahida BaqarDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Rockville, Maryland.
Inci YildirimDepartments of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Carol KaoDepartments of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Nadine RouphaelDepartments of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Andi L ShaneDepartments of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Kathryn EdwardsDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Effect of Nutrition, Immunity, and Vaccines on Pediatric Enteric InfectionsK01AI087724 · NIAID · EMORY UNIVERSITY · PI LEON, JUAN S. · 2010 to 2014
$595k
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Data from 1174 infants enrolled in a previous rotavirus vaccine study were analyzed to determine the effect of antibiotic exposure (from 14 days before to 7 days after vaccination) on rotavirus serum immunoglobulin A (IgA) responses. Serum IgA responses 1 month after the completion of vaccination were similar among antibiotic-exposed and nonexposed infants.

Indexed as

Administration, OralAnti-Bacterial AgentsChildFemaleHumansImmunoglobulin AMaleRotavirus InfectionsRotavirus VaccinesAnti-Bacterial AgentsImmunoglobulin ARotavirus Vaccinesantibioticmicrobiomepediatricrotavirusserology

Identifiers

PMID31237948
PMCPMC7495907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.