Evidence map›Paper›PMID 31237310›Full record

ArticleThe Journal of frailty & aging2019

Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018.

J Muscedere, P M Kim, J Afilalo, C Balion, V E Baracos, D Bowdish, M Cesari, J D Erusalimsky, T Fülöp, G Heckman and 12 more

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in The Journal of frailty & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. High frailty index scores predict mortality and changes in blood-based biomarkers in aging female mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Foundations and Strategic Vision of the Canadian Translational Geroscience Network.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  3. Article
  4. Review
  5. Intersecting Genetics of Frailty and Cardiovascular Disease.The journal of nutrition, health & aging · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 5 countries.

J MuscedereDr. John Muscedere, Kingston Health Sciences Centre, 76 Stuart Street, Kingston, Ontario, Canada, Email: john.muscedere@kingstonhsc.ca.
P M Kim
J Afilalo
C Balion
V E Baracos
D Bowdish
M Cesari
J D Erusalimsky
T Fülöp
G Heckman
S E Howlett
R G Khadaroo
J L Kirkland
L Rodriguez Mañas
E Marzetti
G Paré
P Raina
K Rockwood
A Sinclair
C Skappak
C Verschoor
S Walter
McMaster University · CADalhousie University · CAHospital Universitario de Getafe · ESUniversity of Alberta · CACardiff Metropolitan University · GBDiabetes UK · GBImpact · CAJewish General Hospital · CAMayo Clinic in Florida · USQueen's University · CAResearch Institute for Aging · CAUniversità Cattolica del Sacro Cuore · ITUniversité de Sherbrooke · CAUniversity of Milan · ITUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Canadian Frailty Network (CFN), a pan-Canadian not-for-profit organization funded by the Government of Canada through the Networks of Centres of Excellence Program, is dedicated to improving the care of older Canadians living with frailty. The CFN has partnered with the Canadian Longitudinal Study on Aging (CLSA) to measure potential frailty biomarkers in biological samples (whole blood, plasma, urine) collected in over 30,000 CLSA participants. CFN hosted a workshop in Toronto on January 15 2018, bringing together experts in the field of biomarkers, aging and frailty. The overall objectives of the workshop were to start building a consensus on potential frailty biomarker domains and identify specific frailty biomarkers to be measured in the CLSA biological samples. The workshop was structured with presentations in the morning to frame the discussions for the afternoon session, which was organized as a free-flowing discussion to benefit from the expertise of the participants. Participants and speakers were from Canada, Italy, Spain, United Kingdom and the United States. Herein we provide pertinent background information, a summary of all the presentations with key figures and tables, and the distillation of the discussions. In addition, moving forward, the principles CFN will use to approach frailty biomarker research and development are outlined. Findings from the workshop are helping CFN and CLSA plan and conduct the analysis of biomarkers in the CLSA samples and which will inform a follow-up data access competition.

Indexed as

BiomarkersAgedCanadaFrail ElderlyFrailtyHumansLongitudinal StudiesPrognosisRisk AssessmentBiomarkersagingbiomarkersCFNCLSAfrailtyfrailty indexolder adultsseniors

Identifiers

PMID31237310
PMCPMC12275670
OpenAlexW2955019644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.