Evidence map›Paper›PMID 31237144›Full record

SynthesisCell transplantation

Cells Involved in Urethral Tissue Engineering: Systematic Review.

Martina Culenova, Stanislav Ziaran, Lubos Danisovic

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Toward Sex-Specific Biomaterials Innovation: A Perspective.ACS biomaterials science & engineering · 2025
    Review
  4. Article
  5. Review
  6. Tissue Engineering for Penile Reconstruction.Bioengineering (Basel, Switzerland) · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Martina CulenovaInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Slovakia.
Stanislav ZiaranDepartment of Urology, Comenius University, Slovakia.
Lubos DanisovicInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Slovakia.ORCID 0000-0002-5074-9621
Comenius University Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The urethra is part of the lower urinary tract and its main role is urine voiding. Its complex histological structure makes urethral tissue prone to various injuries with complicated healing processes that often lead to scar formation. Urethral stricture disease can affect both men and women. The occurrence of this pathology is more common in men and thus are previous research has been mainly oriented on male urethra reconstruction. However, commonly used surgical techniques show unsatisfactory results because of complications. The new and progressively developing field of tissue engineering offers promising solutions, which could be applied in the urethral regeneration of both men´s and women´s urethras. The presented systematic review article offers an overview of the cells that have been used in urethral tissue engineering so far. Urine-derived stem cells show a great perspective in respect to urethral tissue engineering. They can be easily harvested and are a promising autologous cell source for the needs of tissue engineering techniques. The presented review also shows the importance of mechanical stimuli application on maturating tissue. Sufficient vascularization and elimination of stricture formation present the biggest challenges not only in customary surgical management but also in tissue-engineering approaches.

Indexed as

Tissue EngineeringAnimalsFemaleHumansMaleStem CellsUrethraUrethral Stricturecellstissue engineeringUrethraurethral stricture

Identifiers

PMID31237144
PMCPMC6767881
OpenAlexW2955711150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.