Evidence map›Paper›PMID 31236899›Full record

ArticleInfection2019

Successful treatment of extra-pulmonary tuberculosis presenting concomitantly with acute myeloid leukemia.

Jaffar A Al-Tawfiq, Adil Al-Khatti

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jaffar A Al-TawfiqSpecialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran Health Center, P. O. Box 76, Room A-420B, Building 61, Dhahran, 31311, Saudi Arabia. jaffar.tawfiq@jhah.com.ORCID http://orcid.org/0000-0002-5752-2235
Adil Al-KhattiHematology-Oncology Unit, Oncology Institute, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Johns Hopkins University · USSaudi Aramco Medical Services Organization · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere were reports of the occurrence of TB during therapy for leukemia with possible complications. In patients with acute leukemia, therapy might be delayed or complicated by the presence of tuberculosis.

methodWe present a patient who was diagnosed with acute leukemia and concomitant tuberculosis.

resultsThe patient's therapy of leukemia had to be delayed and he had relapse of leukemia but was subsequently treated successfully for both diseases despite a prolonged culture positivity for tuberculosis. He required a prolonged course of therapy and additional secondary anti-tuberculosis therapy.

conclusionsThe possibility of tuberculosis should be considered in the differential diagnosis of patients with pneumonia, persistent fever, and those with focal signs or symptoms suggestive of tuberculosis. Despite having a sensitive organism, the infection was difficult to treat, even with the addition of two second-line drugs. The standard anti-tuberculosis therapy is usually adequate, but response may be slow, and inadequate even if the organism is sensitive requiring the addition of second-line agents.

Indexed as

Acute DiseaseAntitubercular AgentsFeverHumansLeukemia, Myeloid, AcuteMaleMiddle AgedTomography, X-Ray ComputedTreatment OutcomeTuberculosisAntitubercular AgentsAcute myeloid leukemiaAMLTBTuberculosis

Identifiers

PMID31236899
OpenAlexW2954313497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.