Evidence map›Paper›PMID 31236832›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Characterization of a highly effective preparation for suppression of myocardial glucose utilization.

Sophia R Larson, Justin A Pieper, Edward A Hulten, Edward P Ficaro, James R Corbett, Venkatesh L Murthy, Richard L Weinberg

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Meta-analysis of the effectiveness of heparin in suppressing physiological myocardial FDG uptake in PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Diagnostic yield of whole-bodyJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  7. Utility of serum ketone levels for assessment of myocardial glucose suppression forJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  8. Effective suppression of myocardial glucose uptake using predesigned low-carbohydrate boxed meals.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  9. Tracking the progress of inflammation with PET/MRI in a canine model of myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  10. Current cardiology reports · 2021
    Review
  11. Review
  12. Correlating cardiac F-18 FDG PET/CT results with intra-operative findings in infectious endocarditis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  14. Article
  15. Diagnostic Performance ofDiagnostics (Basel, Switzerland) · 2020
    Article
  16. Seeking clarity: Insights from a highly effective preparation protocol for suppressing myocardial glucose uptake for PET imaging of cardiac inflammation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sophia R LarsonDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
Justin A PieperDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
Edward A HultenFort Belvoir Community Hospital, VA and Uniformed Services University, Bethesda, MD, USA.
Edward P FicaroINVIA Medical Imaging Solutions, Ann Arbor, MI, USA.
James R CorbettDivision of Cardiovascular Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
Venkatesh L MurthyDivision of Cardiovascular Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
Richard L WeinbergDivision of Cardiovascular Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA. rlweinbe@med.umich.edu.

Funding

Implications of metabolism on healthy aging in African and Caucasian Americans: the Health ABC studyR01AG059729 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, NEWMAN, ANNE B. · 2018 to 2022
$3.1M
Molecular markers of early cardiometabolic health transitions in the CARDIA studyR01HL136685 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, SHAH, RAVI · 2017 to 2021
$2.6M
NHLBI NIH HHS R01 HL136685NIA NIH HHS R01 AG059729
6 · The paper itself

Abstract

backgroundWith appropriate protocols, F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) can visualize myocardial inflammation. Optimal protocols and normative myocardial FDG uptake values are not well-established.

methodsWe evaluated 111 patients referred for inflammation cardiac FDG PET/CT. Patients followed a low-carbohydrate, high-fat diet for 36 hours before imaging and received unfractionated heparin. Glucose and fatty acid metabolism biomarkers were obtained. Mean blood pool and maximum myocardial uptake (SUV

resultsAdequate suppression of myocardial FDG uptake occurred in 95% of patients (n = 106). Myocardial SUV

conclusionsPatients following intensive metabolic preparation have myocardial FDG SUV

Indexed as

Fluorodeoxyglucose F18AgedBiomarkersFemaleGlucoseHeartHumansImage Processing, Computer-AssistedInflammationMaleMiddle AgedMyocardiumPeptidesPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsBiomarkersFluorodeoxyglucose F18GlucosePeptidesRadiopharmaceuticalsFDGmetabolic preparationmyocardial inflammationPET/CT

Identifiers

PMID31236832
PMCPMC6928445

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.