Evidence map›Paper›PMID 31236137›Full record

ArticleBiotechnology for biofuels2019

The genetic basis of 3-hydroxypropanoate metabolism in

Christian Arenas-López, Jessica Locker, Diego Orol, Frederik Walter, Tobias Busche, Jörn Kalinowski, Nigel P Minton, Katalin Kovács, Klaus Winzer

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Pressure Dependent Changes in COBiotechnology journal · 2026
    Article
  2. Review
  3. Polyhydroxyalkanoate Copolymer Production by RecombinantBioengineering (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Efficient Knocking Out of the Organophosphorus Insecticides Degradation GeneInternational journal of molecular sciences · 2023
    Article
  6. Improving carbon monoxide tolerance ofFrontiers in bioengineering and biotechnology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Christian Arenas-López1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Jessica Locker1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Diego Orol1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Frederik Walter1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Tobias Busche2Center for Biotechnology (CeBiTec), Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Jörn Kalinowski2Center for Biotechnology (CeBiTec), Bielefeld University, Universitätsstraße 27, 33615 Bielefeld, Germany.
Nigel P Minton1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Katalin Kovács1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Klaus Winzer1BBSRC/EPSCR Synthetic Biology Research Centre (SBRC), School of Life Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD UK.ORCID 0000-0002-3956-8096
Engineering and Physical Sciences Research Council · GBBielefeld University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background3-Hydroxypropionic acid (3-HP) is a promising platform chemical with various industrial applications. Several metabolic routes to produce 3-HP from organic substrates such as sugars or glycerol have been implemented in yeast, enterobacterial species and other microorganisms. In this study, the native 3-HP metabolism of

resultsWhen testing

conclusionsThree different (methyl)malonate semialdehyde dehydrogenases contribute to 3-HP breakdown in

Indexed as

3-Hydroxypropionic acidCarbon fixationCo-metabolismCupriavidus necatorMalonate semialdehyde dehydrogenaseMetabolic engineeringRalstonia eutrophaValineβ-alanine

Identifiers

PMID31236137
PMCPMC6572756
OpenAlexW2949607855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.