ArticleNature ecology & evolution2019
Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease.
Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- More evidence for widespread antagonistic pleiotropy in polymorphic disease alleles.Frontiers in genetics · 2024Review
- Evidence for the role of selection for reproductively advantageous alleles in human aging.Science advances · 2023Article
- The evolution of aging and lifespan.Trends in genetics : TIG · 2023Review
- miR-71 mediates age-dependent opposing contributions of the stress-activated kinase KGB-1 in Caenorhabditis elegans.Genetics · 2021Article
- Evolutionary demographic models reveal the strength of purifying selection on susceptibility alleles to late-onset diseases.Nature ecology & evolution · 2021Article
- The shared genetic architecture of schizophrenia, bipolar disorder and lifespan.Human genetics · 2021Article
- Antagonistic Pleiotropy in Human Disease.Journal of molecular evolution · 2020Review
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Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.