ArticleScientific reports2019
Field trial of a probiotic bacteria to protect bats from white-nose syndrome.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Towards evidence-based conservation of subterranean ecosystems.Biological reviews of the Cambridge Philosophical Society · 2022Pooled it
- Relationship of temperature with declines and persistence of Myotis lucifugus after white-nose syndrome.Conservation biology : the journal of the Society for Conservation Biology · 2026Article
- Bat skin microbiome and the association of ecoregion and bat species that impacted isolation of members with bioactivity against Pseudogymnoascus destructans.Animal microbiome · 2026Article
- Role of anti-Applied and environmental microbiology · 2026Article
- Ecosystem technology (ecotech): Harnessing natural processes to address global challenges.Science advances · 2026Review
- Occupancy and activity patterns of a newly white-nose syndrome infected species in Texas, the Tricolored Bat (Journal of mammalogy · 2026Article
- Inhibitory and synergistic effects of volatile organic compounds from bat caves againstmSystems · 2026Article
- How "pro" are probiotics for wildlife species? Novel data, lack of evidence, and future directions.ISME communications · 2026Article
- Metagenomic analysis of the gut microbiota inFrontiers in microbiology · 2026Article
- Identification of Opportunistic Pathogens on the Skin of Salamanders for Use as Molecular Targets of a De Novo Design of Multitarget Anti-International journal of microbiology · 2026Article
- Phylogenetic influence on gut microbiome diversity within an African herbivore community.BMC ecology and evolution · 2025Article
- Differential Population Responses to White-Nose Syndrome Between Two Michigan Bat Hibernacula Are Not due to Differences in Host Susceptibility.Ecology and evolution · 2025Article
- A Palearctic view of a bat fungal disease.Conservation biology : the journal of the Society for Conservation Biology · 2025Review
- Strategies and limitations of the bat immune response toFrontiers in immunology · 2025Review
- Pseudogymnoascus destructans invasion stage impacts the skin microbial functions of highly vulnerable Myotis lucifugus.FEMS microbiology ecology · 2024Article
- Microbiota diversity and anti-Applied and environmental microbiology · 2024Article
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- Incomplete immunity in a natural animal-microbiota interaction selects for higher pathogen virulence.Current biology : CB · 2024Article
- When the host's away, the pathogen will play: the protective role of the skin microbiome during hibernation.Animal microbiome · 2023Review
- Delivery mechanism can enhance probiotic activity against honey bee pathogens.The ISME journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tools for reducing wildlife disease impacts are needed to conserve biodiversity. White-nose syndrome (WNS), caused by the fungus Pseudogymnoascus destructans, has caused widespread declines in North American bat populations and threatens several species with extinction. Few tools exist for managers to reduce WNS impacts. We tested the efficacy of a probiotic bacterium, Pseudomonas fluorescens, to reduce impacts of WNS in two simultaneous experiments with caged and free-flying Myotis lucifugus bats at a mine in Wisconsin, USA. In the cage experiment there was no difference in survival between control and P. fluorescens-treated bats. However, body mass, not infection intensity, predicted mortality, suggesting that within-cage disturbance influenced the cage experiment. In the free-flying experiment, where bats were able to avoid conspecific disturbance, infection intensity predicted the date of emergence from the mine. In this experiment treatment with P. fluorescens increased apparent overwinter survival five-fold compared to the control group (from 8.4% to 46.2%) by delaying emergence of bats from the site by approximately 32 days. These results suggest that treatment of bats with P. fluorescens may substantially reduce WNS mortality, and, if used in combination with other interventions, could stop population declines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.