ArticleScientific reports2019
The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Mosquito-based malaria control through genetic, microbial and immunological innovations.Nature reviews. Microbiology · 2026Review
- Article
- Bacterially expressed recombinant TMOF induces mortality and gut microbial alterations in Aedes albopictus larvae.Scientific reports · 2026Article
- Diversity of culturable gut bacteria and their role in conferring resistance to alpha-cypermethrin in field populations ofFrontiers in microbiology · 2026Article
- Transplant of cryopreserved mosquito gut microbiota reveals strain-specific patterns of microbial acquisition and assembly.ISME host microbe · 2026Article
- Environmental persistence and transmission dynamics ofApplied and environmental microbiology · 2025Article
- Impact of insecticide resistance on controlling mosquito vectors and its potential contribution to behavioural modifications.Malaria journal · 2025Review
- Assessing gut microbiota diversity and functional potential in resistant and susceptible strains of the mediterranean fruit fly.Scientific reports · 2025Article
- Evidence of microbiome contribution to the escalation of pyrethroid resistance in the major malaria vectors Anopheles gambiae s.s. and Anopheles funestus s.s.BMC microbiology · 2025Article
- The mosquitocidal activity of isoxazoline derivatives afoxolaner, lotilaner, and fluralaner are not affected by mosquito sugar or antibiotic treatment.Scientific reports · 2025Article
- Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors.International journal of molecular sciences · 2025Review
- Insecticide resistant Anopheles from Ethiopia but not Burkina Faso show a microbiota composition shift upon insecticide exposure.Parasites & vectors · 2025Article
- Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a host-dependent manner.Scientific reports · 2024Article
- Intestinal commensal bacteria promote Bactrocera dorsalis larval development through the vitamin B6 synthesis pathway.Microbiome · 2024Article
- MosAIC: An annotated collection of mosquito-associated bacteria with high-quality genome assemblies.PLoS biology · 2024Article
- The Effect of Larval Exposure to Heavy Metals on the Gut Microbiota Composition of AdultTropical medicine and infectious disease · 2024Article
- Mosquito Gut Microbiota: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Generation of specific immune memory by bacterial exposure in the major malaria vectorCurrent research in insect science · 2024Article
- Impact of the microbiome on mosquito-borne diseases.Protein & cell · 2023Review
- Geographical survey of the mycobiome and microbiome of Southern California glassy-winged sharpshooters.mSphere · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota of mosquitoes is a crucial determinant of their fitness. As such, the biology of the gut microbiota of Anopheles arabiensis, a major malaria vector of Southern Africa, was investigated. Two laboratory strains of An. arabiensis were used; SENN, an insecticide susceptible strain, and SENN-DDT, a resistant strain. The strains were supplemented with either non-commensal bacteria or antibiotics via a sucrose source to sterilize the gut. The strains were fed the broad-spectrum bactericidal antibiotic gentamicin, or a preferentially gram-positive bactericidal (vancomycin), gram-negative bactericidal (streptomycin) or broad-spectrum bacteriostatic (erythromycin), either by sugar supplementation or by artificially-spiked blood-meal. The effects on adult mosquito longevity and insecticide resistance phenotype were assessed. Bacteria from the midgut of both strains were characterised by MALDI-TOF mass spectroscopy. Bactericidal antibiotics increased longevity in SENN-DDT. Bacterial supplementation increased insecticide tolerance. Antibiotic supplementation via sugar decreased tolerance to the insecticides deltamethrin and malathion. Blood-supplemented vancomycin decreased insecticide resistance, while gentamicin and streptomycin increased resistance. SENN showed a greater gut bacterial diversity than SENN-DDT, with both strains dominated by Gram-negative bacteria. This study suggests a crucial role for bacteria in An. arabiensis life history, and that gut microflora play variable roles in insecticide resistant and susceptible mosquitoes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.