ArticleScientific reports2019
Left hemisphere enhancement of auditory activation in language impaired children.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 53 citations in OpenAlex.
- MEG Evidence of Concurrent Bilateral and Hemisphere-Specific Developmental Patterns in Auditory Cortex.Developmental science · 2026Article
- Passive OPM-MEG paradigm reveals altered brain network organization in children with DLD.iScience · 2026Article
- Long-latency auditory evoked responses across species show increased amplitude during early life.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Divergent auditory activation in relation to inhibition task performance in children and adults.Human brain mapping · 2023Article
- Attentional modulation of interhemispheric (a)symmetry in children with developmental language disorder.Scientific reports · 2022Article
- Neural Mechanisms Underlying Human Auditory Evoked Responses Revealed By Human Neocortical Neurosolver.Brain topography · 2022Article
- Magnetic Source Imaging and Infant MEG: Current Trends and Technical Advances.Brain sciences · 2019Review
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Authors and funding
4 authors at 3 institutions in 1 country.
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Abstract
Specific language impairment (SLI) is a developmental disorder linked to deficient auditory processing. In this magnetoencephalography (MEG) study we investigated a specific prolonged auditory response (N250m) that has been reported predominantly in children and is associated with level of language skills. We recorded auditory responses evoked by sine-wave tones presented alternately to the right and left ear of 9-10-year-old children with SLI (n = 10) and children with typical language development (n = 10). Source analysis was used to isolate the N250m response in the left and right hemisphere. In children with language impairment left-hemisphere N250m responses were enhanced compared to those of controls, while no group difference was found in the right hemisphere. Consequently, language impaired children lacked the typical right-ward asymmetry that was found in control children. Furthermore, left but not right hemisphere N250m responses correlated positively with performance on a phonological processing task in the SLI group exclusively, possibly signifying a compensatory mechanism for delayed maturation of language processing. These results suggest that enhanced left-hemisphere auditory activation reflects a core neurophysiological manifestation of developmental language disorders, and emphasize the relevance of this developmentally specific activation pattern for competent language development.
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