Evidence map›Paper›PMID 31235638›Full record

ArticleInfection and immunity2019

Stenotrophomonas maltophilia Encodes a VirB/VirD4 Type IV Secretion System That Modulates Apoptosis in Human Cells and Promotes Competition against Heterologous Bacteria, Including Pseudomonas aeruginosa.

Megan Y Nas, Richard C White, Ashley L DuMont, Alberto E Lopez, Nicholas P Cianciotto

Abstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. A quorum-sensing molecule fromProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Frontiers in microbiology · 2026
    Article
  9. Manganese homeostasis supportsCurrent research in microbial sciences · 2026
    Article
  10. Isolation and identification ofFrontiers in cellular and infection microbiology · 2026
    Article
  11. Article
  12. Genetic Diversity ofPathogens (Basel, Switzerland) · 2025
    Article
  13. Microbiology spectrum · 2025
    Article
  14. Draft genome sequences ofMicrobiology resource announcements · 2025
    Article
  15. Article
  16. First Report ofAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megan Y NasDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Richard C WhiteDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Ashley L DuMontDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Alberto E LopezDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Nicholas P CianciottoDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA n-cianciotto@northwestern.edu.

Funding

Mentoring For Success: Developing Fundamental Skills For Biomedical ResearchR25GM079300 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCGEE, RICHARD · 2007 to 2020
$6.6M
TRAINING PROGRAM IN IMMUNOLOGY &MOLECULAR PATHOGENESIST32AI007476 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Edward Benjamin Thorp · 1996 to 2026
$6.6M
Stenotrophomonas Maltophilia Type IV Secretion: Modulator of Both Host-Cell Apoptosis and Interbacterial KillingR21AI139596 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 2019 to 2020
$417k
Virulence Mechanisms of the Emerging Pathogen Stenotrophomonas maltophiliaR21AI117082 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 2015 to 2016
$411k
NIAID NIH HHS R21 AI117082NIAID NIH HHS R21 AI139596NIAID NIH HHS T32 AI007476NIGMS NIH HHS R25 GM079300
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisBacterial ProteinsCystic FibrosisHumansMacrophagesPseudomonas aeruginosaStenotrophomonas maltophiliaType IV Secretion SystemsVirulence FactorsBacterial ProteinsType IV Secretion SystemsVirulence Factorsapoptosisbacterial competitionepithelial cellsmacrophagesPseudomonasPseudomonas aeruginosaStenotrophomonasStenotrophomonas maltophiliatype IV secretionXanthomonas

Identifiers

PMID31235638
PMCPMC6704607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.