ArticleProceedings of the National Academy of Sciences of the United States of America2019
Single-cell genomics unveiled a cryptic cyanobacterial lineage with a worldwide distribution hidden by a dinoflagellate host.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- A genomic view of Earth's biomes.Nature reviews. Genetics · 2026Review
- The chitin raft hypothesis for the colonization of the open ocean by cyanobacteria.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Experimental assessment of interactions between marine bacteria and model protists: from predator-prey relationships to bacterial-mediated lysis.Applied and environmental microbiology · 2025Article
- Phycobacteria Biodiversity, Selected Isolation, and Bioactivity Elucidation of New Bacterial Species of Highly Toxic Marine DinoflagellateMicroorganisms · 2025Article
- Marked Genome Reduction Driven by a Parasitic Lifestyle: Two Complete Genomes of Endosymbiotic Bacteria Possibly Hosted by a Dinoflagellate.Microbes and environments · 2025Article
- Microbial function in food fermentations: Current research and future directions.Current research in microbial sciences · 2025Article
- Review
- Convergent reductive evolution of cyanobacteria in symbiosis with Dinophysiales dinoflagellates.Scientific reports · 2024Article
- Chitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A robust approach to estimate relative phytoplankton cell abundances from metagenomes.Molecular ecology resources · 2023Article
- Taxonomic and Bioactivity Characterizations ofMarine drugs · 2022Article
- Beyond Soil-Dwelling Actinobacteria: Fantastic Antibiotics and Where to Find Them.Antibiotics (Basel, Switzerland) · 2022Review
- Cyanobiont genetic diversity and host specificity of cyanobiont-bearing dinoflagellate Ornithocercus in temperate coastal waters.Scientific reports · 2021Article
- Tara Oceans: towards global ocean ecosystems biology.Nature reviews. Microbiology · 2020Review
- Evolutionary Mechanisms of Long-Term Genome Diversification Associated With Niche Partitioning in Marine Picocyanobacteria.Frontiers in microbiology · 2020Article
- Genomics reveals alga-associated cyanobacteria hiding in plain sight.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
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8 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Cyanobacteria are one of the most important contributors to oceanic primary production and survive in a wide range of marine habitats. Much effort has been made to understand their ecological features, diversity, and evolution, based mainly on data from free-living cyanobacterial species. In addition, symbiosis has emerged as an important lifestyle of oceanic microbes and increasing knowledge of cyanobacteria in symbiotic relationships with unicellular eukaryotes suggests their significance in understanding the global oceanic ecosystem. However, detailed characteristics of these cyanobacteria remain poorly described. To gain better insight into marine cyanobacteria in symbiosis, we sequenced the genome of cyanobacteria collected from a cell of a pelagic dinoflagellate that is known to host cyanobacterial symbionts within a specialized chamber. Phylogenetic analyses using the genome sequence revealed that the cyanobacterium represents an underdescribed lineage within an extensively studied, ecologically important group of marine cyanobacteria. Metagenomic analyses demonstrated that this cyanobacterial lineage is globally distributed and strictly coexists with its host dinoflagellates, suggesting that the intimate symbiotic association allowed the cyanobacteria to escape from previous metagenomic studies. Furthermore, a comparative analysis of the protein repertoire with related species indicated that the lineage has independently undergone reductive genome evolution to a similar extent as
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