Evidence map›Paper›PMID 31235559›Full record

ArticleAntimicrobial agents and chemotherapy2019

Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin.

Samira Dahesh, Brian Wong, Victor Nizet, George Sakoulas, Truc T Tran, Samuel L Aitken

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. ManagingEClinicalMedicine · 2026
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  13. Daptomycin versus Glycopeptides for the Treatment ofAntibiotics (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Continued Dosing of Oritavancin for Complicated Gram-Positive Infections.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2020
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Samira DaheshUniversity of California San Diego School of Medicine, La Jolla, California, USA.
Brian WongDivision of Infectious Diseases, Loma Linda Jerry L. Pettis Memorial Veterans Medical Center, Loma Linda, California, USA.
Victor NizetUniversity of California San Diego School of Medicine, La Jolla, California, USA.ORCID 0000-0003-3847-0422
George SakoulasUniversity of California San Diego School of Medicine, La Jolla, California, USA gsakoulas@ucsd.edu slaitken@mdanderson.org.
Truc T TranCenter for Antimicrobial Resistance and Microbial Genomics (CARMiG), UTHealth McGovern Medical School, Houston, Texas, USA.
Samuel L AitkenCenter for Antimicrobial Resistance and Microbial Genomics (CARMiG), UTHealth McGovern Medical School, Houston, Texas, USA gsakoulas@ucsd.edu slaitken@mdanderson.org.
University of California San Diego · USJerry L. Pettis Memorial VA Medical Center · USThe University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Systems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseU54HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIGAM, SANJAY K · 2016 to 2018
$2.2M
Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseP50HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CAPPARELLI, EDMUND VINCENT, NIZET, VICTOR · 2019 to 2020
$1.4M
NIAID NIH HHS R37 AI052453NIAID NIH HHS U01 AI124316NICHD NIH HHS P50 HD090259NICHD NIH HHS U54 HD090259
6 · The paper itself

Abstract

Weekly oritavancin plus ampicillin continuous infusion combination therapy was used to successfully treat a deep spine vancomycin-resistant

Indexed as

AmpicillinAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialDrug SynergismEnterococcus faeciumGram-Positive Bacterial InfectionsHumansLipoglycopeptidesMaleMicrobial Sensitivity TestsMiddle AgedOsteomyelitisVancomycinVancomycin-Resistant EnterococciAmpicillinAnti-Bacterial AgentsLipoglycopeptidesoritavancinVancomycinampicillinoritavancinvancomycin-resistant Enterococcus faecium

Identifiers

PMID31235559
PMCPMC6591586
OpenAlexW2953132202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.